RECENT PUBLICATIONS citing the generation of antibody custom-made by YenZym; publications related to post-translational modification-specific antibodies are in the last portion of the list.


  1. Garza D, Riley SP, Martinez JJ. Expression of Rickettsia Adr2 protein in E. coli is sufficient to promote resistance to complement-mediated killing, but not adherence to mammalian cells. PLOS One. 2017;

  2. Yin G, Stephenson HT, Yang J, Li X, Armstrong SM, Heibeck TH, Tran C, Masikat MR, Zhou S, Stafford RL, Yam AY, Lee J, Steiner AR, Gill A, Penta K, Pollitt S, Baliga R, Murray CJ, Thanos CJ, McEvoy LM, Sato AK, and Hallam TJ. RF1 attenuation enables efficient non-natural amino acid incorporation for production of homogeneous antibody drug conjugates. Scientific Reports. 2017; 3026; doi:10.1038/s41598-017-03192-z.

  3. Quinn ME, Goh Q, Kurosaka M, Gamage DG, Petrany MJ, Prasad V, and Millay DP. Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development. Nature Communications. 2017; 15665; doi:10.1038/ncomms15665.

  4. Gheldof N, Moco S, Chabert C, Teav T, Barron D, and Hager J. Role of sulfotransferases in resveratrol metabolism in human adipocytes. Molecular Nutrition and Food Research. 2017; DOI: 10.1002/mnfr.201700020.

  5. Bussiere R, Lacampagne A, Reiken S, Liu X, Scheuerman V, Zalk R, Martin C, Checler F, Marks AR, and Chami M. Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor. Journal of Biological Chemistry. 2017; doi: 10.1074/jbc.M116.743070.

  6. Luongo TS, Lambert JP, Gross P, Nwokedi M, Lombardi AA, Shanmughapriya S, Carpenter AC, Kolmetzky D, Gao E, van Berlo JH, Tsai EJ, Molkentin JD, Chen X, Madesh M, Houser SR and Elrod JW. The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability. Nature. 2017; 545: 93-97. doi:10.1038/nature22082.

  7. Kurlawala Z, Shah PP, Shah C, and Beverly LJ. The STI and UBA Domains of UBQLN1 Are Critical Determinants of Substrate Interaction and Proteostasis. Journal of Cellular Biochemistry. 2017; DOI: 10.1002/jcb.25880.

  8. Soh YQS, Mikedis MM, Kojima M, Godfrey AK, de Rooij DG, and Page DC. Meioc maintains an extended meiotic prophase I in mice. PLOS Genetics. 2017;

  9. Anderson KA, Huynh FK, Kelsey Fisher-Wellman K, Stuart JD, Peterson BS, Douros JD, Wagner GR, Thompson JW, Madsen AS, Green MF, Sivley RM, Ilkayeva OR, Stevens RD, Backos DS, Capra JA, Olsen CA, Campbell JE, Muoio DM, Grimsrud PA, and Hirschey MD. SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion. Cell Metabolism. 2017; 25(4): 838-855.e15.

  10. Wagner GR, Bhatt DP, O’Connell TM, Thompson JW, Dubois LG, Backos DS, Yang H, Mitchell GA, Ilkayeva OR, Stevens RD, Grimsrud PA, and Hirschey MD. A Class of Reactive Acyl-CoA Species Reveals the Non-enzymatic Origins of Protein Acylation. Cell Metabolism. 2017; 25(4): 823-837.e8.

  11. Yuen CYL, Wang P, Kang B, Matsumoto K, and Christopher DA. A Non-Classical Member of the Protein Disulfide Isomerase Family, PDI7 of Arabidopsis thaliana, Localizes to the cis-Golgi and Endoplasmic Reticulum Membranes . Plant and Cell Physiology. 2017; 58(6): 1103-1117.

  12. Wang Y, Gao H, Shi C, Erhardt PW, Pavlovsky A, Soloviev DA, Bledzka K, Ustinov V, Zhu L, Qin J, Munday AD, Lopez J, Plow E, and Simon DI. Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα. Nature Communications. 2017; doi:10.1038/ncomms15559.

  13. Boutant M, Kulkarni SS, Joffraud M, Ratajczak J, Valera-Alberni M, Combe R, Zorzano A, and Cantó C. Mfn2 is critical for brown adipose tissue thermogenic function. The Embo Journal. 2017; DOI: 10.15252/embj.201694914.

  14. Alfaro-Aco R, Thawani A, and Petry S. Structural analysis of the role of TPX2 in branching microtubule nucleation. The Journal of Cell Biology. 2017; DOI: 10.1083/jcb.201607060.

  15. Lees JA, Messa M, Sun EW, Wheeler H, Torta F, Wenk MR, De Camilli P, and Reinisch KM. Lipid transport by TMEM24 at ER–plasma membrane contacts regulates pulsatile insulin secretion. Science. 2017. 355(6326): 6171. DOI: 10.1126/science.aah6171.

  16. Fédry J, Liu Y, Péhau-Arnaudet G, Pei J, Li W, Tortorici MA, Traincard F, Meola A, Bricogne G, Grishin NV, Snell WJ, Rey FA, and Krey T. The Ancient Gamete Fusogen HAP2 Is a Eukaryotic Class II Fusion Protein. Cell. 2017; 168(5): 904-915; DOI:

  17. Goh Q and Millay DP. Requirement of myomaker-mediated stem cell fusion for skeletal muscle hypertrophy. eLife. 2017; 10.7554/eLife.20007.

  18. Wang N, She Z, Ingar Z, Martic S, and Kraatz H-B. A Bioorganometallic Approach to Study Histidine Kinase Autophosphorylations. Chemistry A European Journal. 2017; DOI: 10.1002/chem.201605253.

  19. Vikram A, Lewarchik CM, Yoon J-Y, Naqvi A, Kumar S, Morgan GM, Jacobs JS, Li Q, Kim Y-R, Kassan M, Liu J, Gabani M, Kumar A, Mehdi H, Zhu X, Guan X, Kutschke W, Zhang X, Boudreau RL, Dai S, Matasic DS, Jung S-B, Margulies KB, Kumar V, Bachschmid MM, London B, Irani K. Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel. Nature Medicine. 2017; 23: 361-367. doi:10.1038/nm.4284.

  20. Lv Z, Rickman KA, Yuan L, Williams K, Selvam SP, Woosley AN, Howe PH, Ogretmen B, Smogorzewska A, and Olsen SK. S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity. Molecular Cell. 2017; 65(4): 699-714. DOI:

  21. Badgandi HB, Hwang S, Shimada IS, Loriot E, and Mukhopadhyay S. Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins. The Journal of Cell Biology. 2017; DOI: 10.1083/jcb.201607095.

  22. Peel N, Iyer J, Naik A, Dougherty MP, Decker M, and O’Connell KF. Protein Phosphatase 1 Down Regulates ZYG-1 Levels to Limit Centriole Duplication. PLOS Genetics. 2017;

  23. Quick AP, Wang Q, Philippen LE, Barreto-Torres G, Chiang DY, Beavers D, Wang G, Khalid M, Reynolds JO, Campbell HM, Showell J, McCauley MD, Scholten A, and Wehrens XHT. SPEG (Striated Muscle Preferentially Expressed Protein Kinase) Is Essential for Cardiac Function by Regulating Junctional Membrane Complex Activity. Circulation Research. 2017; 120:110-119.

  24. Medley JC, Kabara MM, Stubenvoll MD, DeMeyer LE, Song MH. Casein kinase II is required for proper cell division and acts as a negative regulator of centrosome duplication in Caenorhabditis elegans embryos. Biology Open. 2017; 6: 17-28; doi: 10.1242/bio.022418.

  25. Chen X, Ma W, Zhang S, Paluch J, Guo W, Dickman DK. The BLOC-1 Subunit Pallidin Facilitates Activity-Dependent Synaptic Vesicle Recycling.eNeuro. 2017; 4(1) ENEURO.0335-16.2017; DOI: 10.1523/ENEURO.0335-16.2017.

  26. Kurlawala Z,Shah PP, Shah C, and Beverly LJ. The STI and UBA Domains of UBQLN1 are Critical Determinants of Substrate Interaction and Proteostasis. Journal of Cellular Biochemistry. 2017; DOI: 10.1002/jcb.25880.

  27. Lopez AY, Wang X, Xu M, Maheshwari A, Curry D, Lam S, Adesina AM, Noebels JL, Sun QQ, and Cooper EC. Ankyrin-G isoform imbalance and interneuronopathy link epilepsy and bipolar disorder. Molecular Psychiatry. 2016; doi:10.1038/mp.2016.233.

  28. Kim K, Hung R, and Perrimon N. miR-263a Regulates ENaC to Maintain Osmotic and Intestinal Stem Cell Homeostasis in Drosophila. Developmental Cell. 2016;

  29. Choudhury SR, Singh AK, McLeod T, Blanchette M, Jang B,Badenhorst P, Kanhere A, and Brogna S. Exon junction complex proteins bind nascent transcripts independently of pre-mRNA splicing in Drosophila melanogaster. eLIFE. 2016; eLife 2016;5:e19881.

  30. Gong J, Yuan Y, Ward A, Kang L, Zhang B, Wu Z, Peng J, Feng Z, and Liu J. The C. elegans Taste Receptor Homolog LITE-1 Is a Photoreceptor. Cell. 2016; 167(5): 1252-1263. DOI:

  31. Newton AA, Schnittker RR, Yu Z, Munday SS, Baumann DP, Neaves WB, and Baumann P. Widespread failure to complete meiosis does not impair fecundity in parthenogenetic whiptail lizards. Development. 2016; doi: 10.1242/dev.141283.

  32. Carmell MA, Dokshin GA, Skaletsky H, Hu Y, van Wolfswinkel JC, Igarashi KJ, Bellott DW, Nefedov M, Reddien PW, Enders GC, Uversky VN, Mello CC, and Page DC. A widely employed germ cell marker is an ancient disordered protein with reproductive functions in diverse eukaryotes. eLIFE. 2016; 5:e19993.

  33. Joshi AS, Huang X, Choudhary V, Levine TP, Hu J, and Prinz WA. A family of membrane-shaping proteins at ER subdomains regulates pre-peroxisomal vesicle biogenesis. The Journal of Cell Biology. 2016; 215(4): 515-529. DOI: 10.1083/jcb.201602064.

  34. Wang Y,Li D, Luo J, Tian G, Zhao LY, and Liao D. Intrinsic cellular signaling mechanisms determine the sensitivity of cancer cells to virus-induced apoptosis. Scientific Reports. 2016; 6, 37213. doi:10.1038/srep37213.

  35. Ratajczak J, Joffraud M, Trammell SAJ, Ras R, Canela N, Boutant M, Kulkarni SS, Rodrigues M, Redpath P, Migaud ME, Auwerx J, Yanes O, Brenner C, and Carles Canto. NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells. Nature Communications. 2016; 7, 13103. doi:10.1038/ncomms13103.

  36. Xie W, Chojnowski A, Boudier T, Lim JSY, Ahmed S, Ser Z, Stewart C, and Burke B. A-type Lamins Form Distinct Filamentous Networks with Differential Nuclear Pore Complex Associations. Current Biology. 2016;

  37. Huang H, Deng Z, Vladimirova O, Wiedmer A, Lu F, Lieberman PM, and Patel DJ. Structural basis underlying viral hijacking of a histone chaperone complex. Nature Communications. 2016; 7, 12707. doi:10.1038/ncomms12707.

  38. Kobayashi-Kinoshita S, Yamakoshi Y, Onuma K, Yamamoto R, and Asada Y. TGF-β1 autocrine signalling and enamel matrix components. Nature Scientific Reports. 2016; doi:10.1038/srep33644.

  39. Stubenvoll M, Medley J, Irwin M, and Song MH. ATX-2, the C. elegans Ortholog of Human Ataxin-2, Regulates Centrosome Size and Microtubule Dynamics. PLOS Genetics. 2016; doi:

  40. Adams Jr. G, Zhou J, Wang W, Wu H, Quan J, Liu Y, Xia P, Wang Z, Zhou S, Jiang J, Mo F, Zhuang X, Thomas K, Hill DL, Aikhionbare FO, He P, Liu X, Ding X, and Yao X. The Microtubule Plus End Tracking Protein TIP150 Interacts with Cortactin to Steer Directional Cell Migration. The Journal of Biological Chemistry. 2016; 291: 20692-20706. doi: 10.1074/jbc.M116.732719.

  41. Kulkarni SS, Joffraud M, Boutant M, Ratajczak J, Gao AW, Maclachlan C, Hernandez-Alvarez MI, Raymond F, Metairon S, Descombes P, Houtkooper RH, Zorzano A, and Cantó C. Mfn1 Deficiency in the Liver Protects Against Diet-Induced Insulin Resistance and Enhances the Hypoglycemic Effect of Metformin. Diabetes. 2016; db151725.

  42. Lee H, Goodarzi H, Tavazoie SF, and Alarcon CR. TMEM2 Is a SOX4-Regulated Gene That Mediates Metastatic Migration and Invasion in Breast Cancer. Cancer Research. 2016; 76(17): 4994-5005. DOI: 10.1158/0008-5472.CAN-15-2322.

  43. Chen X, Negi SS, Liao S,Gao V, Braun W, and Dreskin SC. Conformational IgE epitopes of peanut allergens Ara h 2 and Ara h 6. Clinical & Experimental Allergy. 2016; DOI: 10.1111/cea.12764.

  44. Bultot L, Jensen TE, Lai Y, Madsen ALB, Collodet C, Kviklyte S, Deak M, Yavari A, Foretz M, Ghaffari S, Bellahcene M, Ashrafian H, Rider MH, Richter EA, and Sakamoto K. A benzimidazole derivative small molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle. American Journal of Physiology. 2016; DOI: 10.1152/ajpendo.00237.2016.

  45. Yuen CYL, Shek R, Kang B, Matsumoto K, Cho EJ, and Christopher DA. Arabidopsis protein disulfide isomerase-8 is a type I endoplasmic reticulum transmembrane protein with thiol-disulfide oxidase activity. BMC Plant Biology. 2016; 16:181. DOI: 10.1186/s12870-016-0869-2.

  46. Hunsperger HM, Ford CJ, Miller JS, Cattolico RA. Differential Regulation of Duplicate Light-Dependent Protochlorophyllide Oxidoreductases in the Diatom Phaeodactylum tricornutum. PLOS One. 2016;

  47. Lei K, Vu HT, Mohan RD, McKinney SA, Seidel CW, Alexander R, Gotting K, Workman JL, Alvarado AS. Egf Signaling Directs Neoblast Repopulation by Regulating Asymmetric Cell Division in Planarians. Developmental Cell. 2016; 38: 1-17. DOI:

  48. Rong Z, Ouyang Z, Magin RS, Marmorstein R, and Yu H. Opposing Functions of the N-terminal Acetyltransferases Naa50 and NatA in Sister-chromatid Cohesion. The Journal of Biological Chemistry. 2016; 291, 19079-19091. doi: 10.1074/jbc.M116.737585.

  49. Choi E, Zhang X, Xing C, and Yu H. Mitotic Checkpoint Regulators Control Insulin Signaling and Metabolic Homeostasis. Cell. 2016; 166(3): 567-581. DOI:

  50. Voelkel-Meiman K, Cheng S, Morehouse SJ, MacQueen AJ. Synaptonemal Complex Proteins of Budding Yeast Define Reciprocal Roles in MutSγ-Mediated Crossover Formation. Genetics. 2016; DOI: 10.1534/genetics.115.182923.

  51. Guo Y, Wang Y, Zhang W, Meltzer S, Zanini D, Yu Y, Li J, Cheng T, Guo Z, Wang Q, Jacobs JS, Sharma Y, Eberl DF, Gopfert MC, Jan LY, Jan YN, and Wang Z. Transmembrane channel-like (tmc) gene regulates Drosophila larval locomotion. PNAS. 2016; 113(26): 7243-7248. doi: 10.1073/pnas.1606537113.

  52. Ori-McKenney KM, McKenney RJ, Huang HH, Li T, Meltzer S, Jan LY, Vale RD, Wiita AP, and Jan YN. Phosphorylation of β-Tubulin by the Down Syndrome Kinase, Minibrain/DYRK1a, Regulates Microtubule Dynamics and Dendrite Morphogenesis. Neuron. 2016; 90(3): 551-563. DOI:

  53. Barmchi MP, Samarasekera G, Gilbert M, Auld VJ, and Zhang B. Magi Is Associated with the Par Complex and Functions Antagonistically with Bazooka to Regulate the Apical Polarity Complex. PLOS One. 2016;

  54. Karve R, Suárez-Román F, and Iyer-Pascuzzi AS. The transcription factor NIN-LIKE PROTEIN 7 (NLP7) controls border-like cell release in Arabidopsis. Plant Physiology. 2016; http:/​/​dx.​doi.​org/​10.​1104/​pp.​16.​00453.

  55. Cobb LJ, Lee C, Xiao J, Yen K, Wong RG, Nakamura HK, Mehta HH, Gao Q, Ashur C, Huffman DM, Wan J, Muzumdar R, Barzilai N, and Cohen P. Naturally occurring mitochondrial-derived peptides are age dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers. Aging. 2016; 8(4): 796-809.

  56. Mackinder LCM, Meyer MT, Mettler-Altmann T, Chen VK, Mitchell MC, Caspari O, Rosenzweig ESF, Pallesen L, Reeves G, Itakura A, Roth R, Sommer F, Geimer S, Mühlhaus T, Schroda M, Goodenough U, Stitt M, Griffiths H, and Jonikas MC. A repeat protein links Rubisco to form the eukaryotic carbon-concentrating organelle. PNAS. 2016; (Suppl) doi: 10.1073/pnas.1522866113.

  57. Hiemstra JA, Lee DI, Chakir K, Gutiérrez‐Aguilar M, Marshall KD, Zgoda PJ, Cruz Rivera N, Dozier DG, Ferguson BS, Heublein DM, Burnett JC, Scherf C, Ivey JR, Minervini G, McDonald KS, Baines CP, Krenz M, Domeier TL, Emter CA. Saxagliptin and Tadalafil Differentially Alter Cyclic Guanosine Monophosphate (cGMP) Signaling and Left Ventricular Function in Aortic‐Banded Mini‐Swine. Journal of the American Heart Association. 2016; doi: 10.1161/JAHA.116.003277.

  58. Pastore N, Brady OA, Diab HI, Martina JA, Sun L, Huynh T, Lim J-A, Zare H, Raben N, Ballabio A, and Puertollano R. TFEB and TFE3 cooperate in the regulation of the innate immune response in activated macrophages. Autophagy. 2016; 12(8): 1240-1258;  .

  59. Kariisa A, Weeks K, Tamayo R. The RNA Domain Vc1 Regulates Downstream Gene Expression in Response to Cyclic Diguanylate in Vibrio cholerae. PLOS One. 2016;

  60. Ono NN, Qin X, Wilson AE, Li G, and Tian L. Two UGT84 Family Glycosyltransferases Catalyze a Critical Reaction of Hydrolyzable Tannin Biosynthesis in Pomegranate (Punica granatum). PLOS ONE. 2016;

  61. Bae H, Chen S, Roche JP, Ai M, Wu C, Diantonio A, and Graf ER. Rab3-GEF controls active zone development at the Drosophila neuromuscular junction. eNeuro. 2016; DOI: 10.1523/ENEURO.0031-16.2016.

  62. Pal K, Hwang S, Somatilaka B, Badgandi H, Jackson PK, DeFea K, and Mukhopadhyay S. Smoothened determines β-arrestin–mediated removal of the G protein–coupled receptor Gpr161 from the primary cilium. The Journal of Cell Biology. 2016; 212(7): 861-875. doi: 10.1083/jcb.201506132.

  63. Ouyang Z, Zheng G, Tomchick DR, Luo X, and Yu H. Structural Basis and IP6 Requirement for Pds5-Dependent Cohesin Dynamics. Science Direct. 2016; doi:10.1016/j.molcel.2016.02.033.

  64. Fish L, Pencheva N, Goodarzi H, Tran H, Yoshida M, Tavazoie SF. Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts. Genes and Development. 2016; 30: 286-398. doi: 10.1101/gad.270645.115.

  65. Du J, Zhang J, He T, Li Y, Su Y, Tie F, Liu M, Harte PJ, and Zhu AJ. Stuxnet Facilitates the Degradation of Polycomb Protein during Development. Developmental Cell. 2016; 37(6): 507-519. DOI:

  66. Hoffman EJ, Turner KJ, Fernandez JM, Cifuentes D, Ghosh, Ijaz S, Jain RA, Kubo F, Bill BR, Baier H, Granato M, Barresi MJF, Wilson SW, Rihel J, State MW, and Giraldez AJ. Estrogens Suppress a Behavioral Phenotype in Zebrafish Mutants of the Autism Risk Gene, CNTNAP2. Neuron. 2016; 89(4): 725-733. DOI:

  67. Nixon M, Stewart-Fitzgibbon R, Fu J, Akhmedov D, Rajendran K, Mendoza-Rodriguez MG, Rivera-Molina YA, Gibson M, Berglund ED, Justice NJ, and Berdeaux R. Skeletal muscle salt inducible kinase 1 promotes insulin resistance in obesity. Molecular Metabolism. 2016; 5(1): 34-46.

  68. Petrova A, Moffett DF. Comprehensive Immunolocalization Studies of a Putative Serotonin Receptor from the Alimentary Canal of Aedes aegypti Larvae Suggest Its Diverse Roles in Digestion and Homeostasis. PLOS One. 2016; DOI: 10.1371/journal.pone.0146587.

  69. Goeres-Miller JD, Liu Y, Williams C, Smith HE, and O'Connell KF. The E2F-DP1 Transcription Factor Complex Regulates Centriole Duplication in C. elegans. G3. 2016; doi: 10.1534/g3.115.025577.

  70. Yun YS, Kim KH, Tschida B, Sachs Z,Noble-Orcutt KE, Moriarity BS, Ai T, Ding R, Williams J, Chen L, Largaespada D, and Kim D. mTORC1 Coordinates Protein Synthesis and Immunoproteasome Formation via PRAS40 to Prevent Accumulation of Protein Stress. Molecular Cell. 2016; 61: 625-639. DOI:

  71. Li X, Zhang R, Patena W, Gang SS, Blum SR, Ivanova N, Yue R, Robertson JM, Lefebvre P, Fitz-Gibbon ST, Grossman AR, and Jonikas MC. An indexed, mapped mutant library enables reverse genetics studies of biological processes in Chlamydomonas reinhardtii. The Plant Cell. 2016; (Suppl) TPC2015-00465-LSB; doi: http:/​/​dx.​doi.​org/​10.​1105/​tpc.​15.​00465.

  72. Zhou Q, Yen A, Rymarczyk G, Asai H, Trengrove C, Aziz N, Kirber MT, Mostoslavsky G, Ikezu T, Wolozin B, and Bolotina VM. Impairment of PARK14-dependent Ca2+ signalling is a novel determinant of Parkinson’s disease. Nature. 2016; doi:10.1038/ncomms10332.

  73. Ling L, Camilleri ET, Helledie T, Samsonraj RM, Titmarsh DM, Chua RJ, Dreesen O, Dombrowski C, Rider DA, Galindo M, Lee I, Hong W, Hui JH, Nurcombe V, van Wijnen AJ, Cool SM. Effect of heparin on the biological properties and molecular signature of human mesenchymal stem cells. Gene. 2016; 576(1): 292-303;

  74. Soupene E, Kao J, Cheng DH, Wang D, Greninger AL, Knudsen GM, DeRisi JL, and Kuypers FA. Association of NMT2 with the acyl-CoA carrier ACBD6 protects the N-myristoyltransferase reaction from palmitoyl-CoA. Journal of Lipid Research. 2015; doi: 10.1194/jlr.M065003.

  75. Bae H, Chen S, Roche JP, Ai M, Wu C, Diantonio A, Graf ER. Rab3-GEF Controls Active Zone Development at the Drosophila Neuromuscular Junction. eNeuro. 2016; DOI: 10.1523/ENEURO.0031-16.2016.

  76. Asundi J, Crocker L, Tremayne J, Chang P, Sakanaka C, Tanguay J, Spencer S, Chalasani S, Luis E, Gascoigne K, Desai R, Raja R, Friedman BA, Haverty PM, Polakis P, and Firestein R. An Antibody–Drug Conjugate Directed against Lymphocyte Antigen 6 Complex, Locus E (LY6E) Provides Robust Tumor Killing in a Wide Range of Solid Tumor Malignancies. Clinical Cancer Research. 2015; 21(14): 3252-3262; DOI: 10.1158/1078-0432.CCR-15-0156.

  77. Calvi A, Wong ASW. Wright G, Wong ESM, Loo TH, Stewart CL, and Brian Burke. SUN4 is essential for nuclear remodeling during mammalian spermiogenesis. Developmental Biology. 2015; 407(2): 321-330.

  78. Meehan TL, Kleinsorge SE, Timmons AK, Taylor JD, and McCall K. Polarization of the epithelial layer and apical localization of integrins are required for engulfment of apoptotic cells in the Drosophila ovary. Disease Models and Mechanisms. 2015; 8: 1603-1614; doi: 10.1242/dmm.021998.

  79. Bauer J, Ozden O, Akagi N, Carroll T, Principe DR, Staudacher JJ, Spehlmann ME, Eckmann L, Grippo PJ, and Jung B. Activin and TGFβ use diverging mitogenic signaling in advanced colon cancer. Molecular Cancer. 2015; 14:182; doi:10.1186/s12943-015-0456-4.

  80. Junttila MR, Mao W, Wang X, Wang B, Pham T, Flygare J, Yu S, Yee S, Goldenberg D, Fields C, Eastham-Anderson J, Singh M, Vij R, Hongo J, Firestein R, Schutten M, Flagella K, Polakis P, and Polson AG. Targeting LGR5+ cells with an antibody-drug conjugate for the treatment of colon cancer. Science Translational Medicine. 2015; 7(314): 314ra186. DOI: 10.1126/scitranslmed.aac7433.

  81. McCleland ML, Soukup TM, Liu SD, Esensten JH, de Sousa e Melo F, Yaylaoglu M, Warming S, Roose-Girma M, and Firestein R. Cdk8 deletion in the ApcMin murine tumour model represses EZH2 activity and accelerates tumourigenesis. The Journal of Pathology. 2015; 237(4): 508-519. DOI: 10.1002/path.4596.

  82. Singh J, Wen X, and Scales SJ.The Orphan G Protein-Coupled Receptor Gpr175 (TPRA40) Enhances Hedgehog Signaling by Modulating cAMP Levels. The Journal of Biological Chemistry. 2015; 290(49): 29663-29675. doi: 10.1074/jbc.M115.665810.

  83. RasmussenTP, Wu Y, Joiner MA, Koval OM, Wilson NR, Luczak ED, Wang Q, Chen B, Gao Z, Zhu Z, Wagner BA, Soto J, McCormick ML, Kutschke W, Weiss RM, Yu L, Boudreau RL, Abel ED, Zhan F, Spitz DR, Buettner GR, Song LS, Zingman LV, and Anderson ME. Inhibition of MCU forces extramitochondrial adaptations governing physiological and pathological stress responses in heart. PNAS. 2015; 112(29): 9129-9134.

  84. Yan D, and Perrimon N. spenito is required for sex determination in Drosophila melanogaster. PNAS. 2015; 112(37): 11606-11611; doi: 10.1073/pnas.1515891112.

  85. Jacobs JZ, Rosado-Lugo JD, Cranz-Mileva S, Ciccaglione KM, Tournier V, and Zaratiegui M. Arrested replication forks guide retrotransposon integration. Science. 2015; (Suppl)349: 1549. DOI: 10.1126/science.aaa3810.

  86. Chojnowski A, Ong PF, Wong ESM, Lim JSY, Mutalif RA, Navasankari R, Dutta B, Yang H, Liow YY, Sze SK, Boudier T, Wright GD, Colman A, Burke B, Stewart CL, Dreesen O. Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria. eLife. 2015; 4:e07759; doi:

  87. Kariisa AT, Grube1 A, and Tamayo R. Two nucleotide second messengers regulate the production of the Vibrio cholerae colonization factor GbpA. BMC Microbiology. 2015; 15:166. doi:10.1186/s12866-015-0506-5.

  88. Neelam S, Chancellor TJ, Li Y, Nickerson JA, Roux KJ, Dickinson RB, and Lele TP. Direct force probe reveals the mechanics of nuclear homeostasis in the mammalian cell. PNAS. 2015; 112(18): 5720-5725. doi: 10.1073/pnas.1502111112.

  89. Cheng S, Ramachandran B, Behrmann A, Shao J, Mead M, Smith C, Krchma K, Arredondo YB, Kovacs A, Kapoor K, Brill LM, Perera R, Williams BO, and Towler DA. Vascular Smooth Muscle LRP6 Limits Arteriosclerotic Calcification in Diabetic LDLR-/- Mice by Restraining Noncanonical Wnt Signals. Circulation Research. 2015; doi: 10.1161/CIRCRESAHA.117.306712.

  90. Ito M, Sferruzzi-Perri AN, Edwards CA, Adalsteinsson BT, Allen SE, Loo T, Kitazawa M, Kaneko-Ishino T, Ishino F, Stewart CL and Ferguson-Smith AC. A trans-homologue interaction between reciprocally imprinted miR-127 and Rtl1 regulates placenta development. Development. 2015; (Suppl) doi: 10.1242/dev.121996.

  91. Youn J, Zhou J, and Cai H. Bone Morphogenic Protein 4 Mediates NOX1-Dependent eNOS Uncoupling, Endothelial Dysfunction, and COX2 Induction in Type 2 Diabetes Mellitus. Molecular Endocrinology. 2015; doi:

  92. Liu F, Li D, Yeung Y, Yu L, Kang I,Cha M, Kim JY, Park C, Watson DK, Wang T, and Choi K. Induction of hematopoietic and endothelial cell program orchestrated by ETS transcription factor ER71/ETV2. EMBO reports. 2015; DOI: 10.15252/embr.201439939.

  93. Dwyer CA, Katoh T, Tiemeyer M, and Matthews RT. Neurons and glia modify RPTPζ/phosphacan with cell-specific O-mannosyl glycans in the developing brain. The Journal of Biological Chemistry. 2015; doi: 10.1074/jbc.M114.614099.

  94. Madarampalli B, Yuan Y, Liu D, Lengel K, Xu Y, Li G, Yang J, Liu X, Lu Z, and Liu DX. ATF5 Connects the Pericentriolar Materials to the Proximal End of the Mother Centriole. Cell. 2015; 162(3): 580-592. DOI:

  95. Goodarzi H, Liu X, Nguyen HCB, Zhang S, Fish L, and Tavazoie SF. Endogenous tRNA-Derived Fragments Suppress Breast Cancer Progression via YBX1 Displacement. Cell. 2015; 161(4): 790-802. DOI:

  96. Ward A, Hong W, Favaloro V, and Liqun Luo. Toll Receptors Instruct Axon and Dendrite Targeting and Participate in Synaptic Partner Matching in a Drosophila Olfactory Circuit. Cell Neuron. 2015; 85(5): 1013-1028.

  97. Balenga NA, Klichinsky M, Xie Z, Chan EC, Zhao M, Jude J, Laviolette M, Panettieri Jr. RA, and Druey KM. A fungal protease allergen provokes airway hyper-responsiveness in asthma. Nature Communications. 2015; doi:10.1038/ncomms7763.

  98. Lee C, Zeng J, Drew BC, Sallam T, Martin-Montalvo A, Wan J, Kim S, Mehta H, Hevener AL, de Cabo R, and Cohen P. The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance. Cell Metabolism. 2015; 21(3): 443-454. DOI:

  99. Shanmughapriya S, Rajan S, Hoffman NE, Zhang X, Guo S, Kolesar JE, Hines KJ, Ragheb J, Jog NR, Caricchio R, Baba Y, Zhou Y, Kaufman BA, Cheung JY, Kurosaki T, Gill DL, and Madesh M. Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU. Science Signaling. 2015; DOI: 10.1126/scisignal.2005673.

  100. Ji Z, Gao H, and Yu H. Kinetochore attachment sensed by competitive Mps1 and microtubule binding to Ndc80C. Science. 2015; 348, 1260 (Supp). DOI: 10.1126/science.aaa4029.

  101. Smith SJ, Gu L, Phipps EA, Dobrolecki LE, Mabrey KS, Gulley P, Dillehay KL, Dong Z, Fields GB, Chen Y, Ann D, Hickey RJ, and Malkas LH. A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer. Molecular Pharmacology. 2015; (Suppl)87(2): 263-276. doi: 10.1124/mol.114.093211.

  102. Wang N, She Z, Lin Y, Martić S, Mann DJ, and Kraatz H. Clickable 5′-γ-Ferrocenyl Adenosine Triphosphate Bioconjugates in Kinase-Catalyzed Phosphorylations. Chemistry - A European Journal. 2015; DOI: 10.1002/chem.201405510.

  103. Lee J, Peng Y, Lin W, and Parrish JZ. Coordinate control of terminal dendrite patterning and dynamics by the membrane protein Raw. Development. 2015; 142: 162-173. doi: 10.1242/dev.113423.

  104. Kim S and Yu H. Multiple assembly mechanisms anchor the KMN spindle checkpoint platform at human mitotic kinetochores. The Journal of Cell Biology. 2015; 208(2): 181-196. doi: 10.1083/jcb.201407074.

  105. Yang J, Wu Z, Renier N, Simon DJ, Uryu K, Park DS, Greer PA, Tournier C, Davis RJ, and Tessier-Lavigne M. Pathological Axonal Death through a MAPK Cascade that Triggers a Local Energy Deficit. Cell. 2015; 160(1-2): 161-176. DOI:

  106. Drake M, Furuta T, Suen KM, Gonzalez G, Liu B, Kalia A, Ladbury JE, Fire AZ, Skeath JB, and Arur S. A Requirement for ERK-Dependent Dicer Phosphorylation in Coordinating Oocyte-to-Embryo Transition in C. elegans. Developmental Cell. 2015; 31(5): 614-628. DOI:

  107. Yang J, Wu Z, Renier N, Simon DJ Uryu K, Park DS, Greer PA, Tournier C, Davis RJ, and Tessier-Lavigne M. Pathological Axonal Death through a MAPK Cascade that Triggers a Local Energy Deficit. Cell. 2015; 160(1-2): 161-176. DOI:

  108. Tsai K, Chan L, Gibeault R, Conn K, Dheekollu J, Domsic J, Marmorstein R, Schang LM, and Lieberman. Viral Reprogramming of the Daxx Histone H3.3 Chaperone during Early Epstein-Barr Virus Infection. Journal of Virology. 2014; doi: 10.1128/JVI.01895-14.

  109. Ulanet DB, Couto K, Jha A, Choe S, Wang A, Woo H, Steadman M, DeLaBarre B, Gross S, Driggers E, Dorsch M, Hurov JB. Mesenchymal Phenotype Predisposes Lung Cancer Cells to Impaired Proliferation and Redox Stress in Response to Glutaminase Inhibition. PLoS ONE. 2014; •DOI: 10.1371/journal.pone.0115144.

  110. Armbruster U, Carrillo LR, Venema K, Pavlovic L, Schmidtmann E, Kornfeld A, Jahns P, Berry JA, Kramer DM, and Jonikas MC. Ion antiport accelerates photosynthetic acclimation in fluctuating light environments. Nature Communications. 2014; doi:10.1038/ncomms6439.

  111. Foulcer SJ, Nelson CM, Quintero MV, Kuberan B, Larkin J, Dours-Zimmermann MT, Zimmermann DR, and Apte SS. Determinants of Versican-V1 Proteoglycan Processing by the Metalloproteinase ADAMTS5. The Journal of Biological Chemistry. 2014; 289: 27859-27873. doi: 10.1074/jbc.M114.573287.

  112. Gorczyca DA, Younger S, Meltzer S, Kim SE, Cheng L, Song W, Lee HY, Jan LY, Jan YN. Identification of Ppk26, a DEG/ENaC Channel Functioning with Ppk1 in a Mutually Dependent Manner to Guide Locomotion Behavior in Drosophila. Cell Reports. 2014; (Suppl) DOI:

  113. Kim H, Colaiácovo MP. ZTF-8 Interacts with the 9-1-1 Complex and Is Required for DNA Damage Response and Double-Strand Break Repair in the C. elegans Germline. PLOS Genetics. 2014; DOI: 10.1371/journal.pgen.1004723.

  114. Zheng C, Tham CTT, Keatings K, Fan S, Liou AYC, Numata Y, Allan D, and Numata M. Secretory Carrier Membrane Protein (SCAMP) Deficiency Influences Behavior of Adult Flies. Frontiers in Cell and Developmental Biology. 2014; DOI=10.3389/fcell.2014.00064.

  115. Midorikawa T, Endow JK, Dufour J, Zhu J, and Inoue K. Plastidic type I signal peptidase 1 is a redox-dependent thylakoidal processing peptidase. The Plant Journal. 2014; doi: 10.1111/tpj.12655.

  116. Yeung J, Ha TJ, Swanson DJ, Choi K, Tong Y, and Goldowitz D. Wls Provides a New Compartmental View of the Rhombic Lip in Mouse Cerebellar Development. The Journal of Neuroscience. 2014; 34(37): 12527-1253734; doi: 10.1523/JNEUROSCI.1330-14.2014.

  117. Sackton KL, Dimova N, Zeng X, Tian W, Zhang M, Sackton TB, Meaders J, Pfaff KL, Sigoillot F, Yu H, Luo X, and King RW. Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C. Nature. 2014; doi:10.1038/nature13660.

  118. Bagley JA, Yan Z, Zhang W, Wildonger J, Jan LY and Jan YN. Double-bromo and extraterminal (BET) domain proteins regulate dendrite morphology and mechanosensory function. Genes and Development. 2014; 28:1940-1956.

  119. Hara K, Zheng G, Qu Q, Liu H, Ouyang Z, Chen Z, Tomchick DR, and Yu H. Structure of cohesin subcomplex pinpoints direct shugoshin-​Wapl antagonism in centromeric cohesion. Nature Structural & Molecular Biology. 2014; 21: 864–870.

  120. Xiong X, Zhao Y, Tang F, Wei D, Thomas D, Wang X, Liu Y, Zheng P, and Sun Y. Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesis. eLIFE. 2014; 10.7554/eLife.02236.

  121. Clay MR, and Halloran MC. Cadherin 6 promotes neural crest cell detachment via F-actin regulation and influences active Rho distribution during epithelial-to-mesenchymal transition. Development. 2014; 141: 2506-2515.

  122. Luo R, Jeong SJ, Yang A, Wen M, Saslowsky DE, Lencer WI, Araç D, Piao X. Mechanism for Adhesion G Protein-Coupled Receptor GPR56-Mediated RhoA Activation Induced By Collagen III Stimulation. PLoS ONE. 2014; DOI: 10.1371/journal.pone.0100043.

  123. Qian W, Miki D, Lei M, Zhu X, Zhang H, Liu Y, Li Y, Lang Z, Wang J, Tang K, Liu R, and Zhu J. Regulation of Active DNA Demethylation by an a-Crystallin Domain Protein in Arabidopsis. Molecular Cell. 2014;

  124. Hiemstra JA, Gutiérrez-Aguilar M, Marshall KD, McCommis KS, Zgoda PJ, Cruz-Rivera N, Jenkins NT, Krenz M, Domeier TL, Baines CP, and Emter CA. A new twist on an old idea part 2: cyclosporine preserves normal mitochondrial but not cardiomyocyte function in mini‐swine with compensated heart failure. Physiological Reports. 2014; DOI: 10.14814/phy2.12050.

  125. Dourado M, Wong E, Hackos DH. Pannexin-1 Is Blocked by Its C-Terminus through a Delocalized Non-Specific Interaction Surface. PLoS ONE. 2014; DOI: 10.1371/journal.pone.0099596.

  126. Hiemstra JA, Gutiérrez-Aguilar M, Marshall KD, McCommis KS, Zgoda PJ, Cruz-Rivera N, Jenkins NT, Krenz M, Domeier TL, Baines CP, and Emter CA. A new twist on an old idea part 2: cyclosporine preserves normal mitochondrial but not cardiomyocyte function in mini-swine with compensated heart failure. Physiological Reports. 2014; 2(6): e12050; doi: 10.14814/phy2.12050.

  127. Gutiérrez-Aguilar M, Douglas DL, Gibson AK, Domeier TL, Molkentin JD, and Baines CP. Genetic manipulation of the cardiac mitochondrial phosphate carrier does not affect permeability transition. Journal of Molecular and Cellular Cardiology. 2014; 72: 316-325.

  128. Hall DD, Wu Y, Domann FE, Spitz DR, Anderson ME. Mitochondrial Calcium Uniporter Activity Is Dispensable for MDA-MB-231 Breast Carcinoma Cell Survival. PLoS ONE. 2014; DOI: 10.1371/journal.pone.0096866.

  129. Heim AE, Hartung O, Rothhämel S, Ferreira E, Jenny A, and Marlow FL.Oocyte polarity requires a Bucky ball-dependent feedback amplification loop. Development. 2014; doi:10.1242/dev.090449.

  130. Shah P, Lockwood W, Saurabh K, Kurlawala Z, Shannon SP, Waigel S, Zacharias W, and Beverly LJ. Ubiquilin1 represses migration and epithelial-to-mesenchymal transition of human non-small cell lung cancer cells. Nature. 2014; doi:10.1038/onc.2014.97.

  131. Yang H, Vallandingham J, Shiu P, Li H, Hunter CP, Mak HY. The DEAD Box Helicase RDE-12 Promotes Amplification of RNAi in Cytoplasmic Foci in C. elegans. Current Biology. 2014; doi: 10.1016/j.cub.2014.01.008.

  132. Arur S, and Schedl T. Generation and purification of highly specific antibodies for detecting post-translationally modified proteins in vivo. Nature Protocols. 2014; 9, 375–395.

  133. Vanlandingham PA, Barmchi MP, Royer S, Green R, Bao H, Reist N, Zhang B. AP180 Couples Protein Retrieval to Clathrin-Mediated Endocytosis of Synaptic Vesicles. Traffic. 2014; doi: 10.1111/tra.12153.

  134. Coleman JA, Zhu X, Djajadi HR, Molday LL, Smith RS, Libby RT, John SWM, and Molday RS. Phospholipid flippase ATP8A2 is required for normal visual and auditory function and photoreceptor and spiral ganglion cell survival. Journal of Cell Science. 2014; doi: 10.1242/​jcs.145052.

  135. Yang J, Weimer RM, Kallop D, Olsen O, Wu Z, Renier N, Uryu K, and Tessier-Lavigne M. Regulation of Axon Degeneration after Injury and in Development by the Endogenous Calpain Inhibitor Calpastatin. Neuron. 2014; DOI:

  136. Riley SP, Patterson JL, Nava S, and Martinez JJ. Pathogenic Rickettsia species acquire vitronectin from human serum to promote resistance to complement-mediated killing. Cellular Microbiology. 2013; 16(6): 849-861.

  137. Melo MB, Nguyen QP, Cordeiro C, Hassan MA, Yang N, McKell R, Rosowski EE, Julien L, Butty V, Dardé M, Ajzenberg D, Fitzgerald K, Young LH, Saeij JPJ. Transcriptional Analysis of Murine Macrophages Infected with Different Toxoplasma Strains Identifies Novel Regulation of Host Signaling Pathways. PLOS Pathogens. 2013; doi: 10.1371/journal.ppat.1003779.

  138. Berthoud VM, Minogue PJ, Yu H, Schroeder R, Snabb JT, and Beyer E. Connexin50D47A decreases levels of fiber cell connexins and impairs lens fiber cell differentiation. Investigative Ophthalmology & Visual Science. 2013; doi: 10.1167/iovs.13-13188.

  139. Cheng CL and Molday RS. Interaction of 4.1G and cGMP-gated channels in rod photoreceptor outer segments. Journal of Cell Science. 2013; doi: 10.1242/jcs.137679.

  140. Voelkel-Meiman K, Taylor LF, Mukherjee P, Humphryes N, Tsubouchi H, MacQueen AJ. SUMO Localizes to the Central Element of Synaptonemal Complex and Is Required for the Full Synapsis of Meiotic Chromosomes in Budding Yeast. PLOS Genetics. 2013; 9(10): e1003837. doi:10.1371/journal.pgen.1003837.

  141. Lee EK, Lian Z, D’Andrea K, Letrero R, Sheng WQ, Liu S, Diehl JN, Pytel D, Barbash O, Schuchter L, Amaravaradi R, Xu X, Herlyn M, Nathanson KL, and Diehl JA. The FBXO4 tumor suppressor functions as a barrier to BrafV600E3 dependent metastatic melanoma. Molecular and Cellular Biology. 2013; 33(22): 4422-4433.

  142. Horn HF, Kim DI, Wright GD, Wong ESM, Stewart CL, Burke B, and Roux KJ. A mammalian KASH domain protein coupling meiotic chromosomes to the cytoskeleton. The Journal of Cell Biology. 2013; doi: 10.1083/jcb.201304004.

  143. Gerdts J, Summers DW, Sasaki Y, DiAntonio A, and Milbrandt J. Sarm1-Mediated Axon Degeneration Requires Both SAM and TIR Interactions. The Journal of Neuroscience. 2013; 33(33): 13569–13580.

  144. Graham WJ, V, Rolfsmeier ML, and Haseltine CA. An archaeal RadA paralog influences presynaptic filament formation. DNA Repair (Amst). 2013; 12(6): 403-413.

  145. Tubon Jr TC, Zhang J, Friedman EL, Jin H, Gonzales ED, Zhou H, Drier D, Gerstner JR, Paulson EA, Fropf R, and Yin JCP. dCREB2-Mediated Enhancement of Memory Formation. The Journal of Neuroscience. 2013; 33(17): 7475-7487.

  146. Ligon LS, Rigel NW, Romanchuk A, Jones CD, and Braunstein M. Suppressor Analysis Reveals a Role for SecY in the SecA2-Dependent Protein Export Pathway of Mycobacteria. Journal of Bacteriology. 2013: doi: 10.1128/JB.00630-13.

  147. Auerbach M, Yan D, Fouts A, Xu M, Estevez A, Austin CD, Bazan F, Feierbach B. Characterization of the guinea pig CMV gH/gL/GP129/GP131/GP133 complex in infection and spread. Virology. 2013; 441(1): 75-84.

  148. Chen X, Taylor DW, Fowler CC, Galan JE, Wang H, and Wolin SL. An RNA Degradation Machine Sculpted by Ro Autoantigen and Noncoding RNA. Cell. 2013; 153(1): 12-14, DOI: 10.1016/j.cell.2013.02.037.

  149. Klemm RW, Norton JP, Cole RA, Li CS, Park SH, Crane MM, Li L, Jin D, Boye-Doe A, Liu TY, Shibata Y, Lu H, Rapoport TA, Farese RV, Blackstone C, Guo Y, Mak HY. A Conserved Role for Atlastin GTPases in Regulating Lipid Droplet Size. Cell Reports. 2013; 3(5): 1465-1475.

  150. Rains MK, Martić S, Freeman D, and Kraatz HB. Electrochemical Investigations into Kinase-Catalyzed Transformations of Tau Protein. ACS Chemical Neuroscience. 2013; 4(8): 1194-1203. DOI: 10.1021/cn400021d.

  151. Dreesen O, Chojnowski A, Ong PF, Zhao TY, Common JE, Lunny D, Lane EB, Lee SJ, Vardy LA, Stewart CL, and Colman A. Lamin B1 fluctuations have differential effects on cellular proliferation and senescence. The Journal of Cell Biology. 2013; 200(5): 605-617.

  152. Minogue PJ, Beyer EC, and Berthoud VM. A connexin50 mutant (CX50fs) that Causes cataracts is unstable, but is rescued by a proteasomal inhibitor. The Journal of Biological Chemistry. 2013; doi: 10.1074/jbc.M113.452847.

  153. Ichinose K, Zhang Z, Koga T, Juang Y, Kis-Tóth K, Sharpe AH, Kuchroo V, Crispín JC, and Tsokos GC. Increased expression of a short splice variant of CTLA-4 exacerbates lupus in MRL/lpr mice. Arthritis Rheum. 2013; 65(3): 764–769.

  154. Kuchay S, Duan S, Schenkein E, A Peschiaroli, Saraf A, Florens L, Washburn MP, and Pagano M. FBXL2- and PTPL1-mediated degradation of p110-free p85β regulatory subunit controls the PI(3)K signalling cascade. Nature Cell Biology. 2013; 15: 472-480.

  155. Tran H, Bustos D, Yeh R,Rubinfeld B, Lam C, Shriver S, Zilberleyb I, Lee MW, Phu L, Sarkar AA, Zohn IE, Wertz IE, Kirkpatrick DS,and Polakis P. HectD1 E3 Ligase Modifies Adenomatous Polyposis Coli (APC) with Polyubiquitin to Promote the APC-Axin Interaction. The Journal of Biological Chemistry. 2013; 288(6): 3753–3767.

  156. Mukhopadhyay S, Wen X, Ratti N, Loktev A, Rangell L, Scales SJ, and Jackson PK. The Ciliary G-Protein-Coupled Receptor Gpr161 Negatively Regulates the Sonic Hedgehog Pathway via cAMP Signaling. Cell. 2013; 152(1): 210-223.

  157. Liew CW, Boucher J, Cheong JK, Vernochet C, Koh H, Mallol C, Townsend K, Langin D, Kawamori D, Hu J, Tseng Y, Hellerstein MK, Farmer SR, Goodyear L, Doria A, Bluher M, Hsu SI, and Kulkarni RN. Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance. Nature Medicine. 2013; 19:217–226.

  158. Melom JE, and Littleton JT. Mutation of a NCKX Eliminates Glial Microdomain Calcium Oscillations and Enhances Seizure Susceptibility. The Journal of Neuroscience. 2013; 33(3): 1169-1178.

  159. Jeong YT, Rossi M, Cermak L, Saraf A, Florens L, Washburn MP, Sung P, Schildkraut CL, and Pagano M. FBH1 promotes DNA double-strand breakage and apoptosis in response to DNA replication stress. The Journal of Cell Biology. 2013; 200(2): 141-149.

  160. Henderson MJ, Richie CT, Airavaara M, Wang Y, and Harvey BK. Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Secretion and Cell Surface Binding are Modulated by KDEL Receptors. The Journal of Biological Chemistry. 2012; doi: 10.1074/jbc.M112.400648.

  161. Eckert C, Boehm M, Carrieri D, Yu J, Dubini A, Nixon PJ, and Maness P. Genetic Analysis of the Hox Hydrogenase in the Cyanobacterium Synechocystis sp. PCC 6803 Reveals Subunit Roles in Association, Assembly, Maturation, and Function. The Journal of Biological Chemistry. 2012; 287:43502-43515.

  162. Garrison JL, Macosko EZ, Bernstein S, Pokala N, Albrecht DR, Bargmann CI. Oxytocin/Vasopressin-Related Peptides Have an Ancient Role in Reproductive Behavior. Science. 2012; 338, 540 Supp. DOI: 10.1126/science.1226201.

  163. Rivera-Cancel G, Motta-Mena LB, and Gardner KH. Identification of Natural and Artificial DNA Substrates for Light-Activated LOV–HTH Transcription Factor EL222. Biochemistry. 2012; 51(50): 10024–10034.

  164. Vonderfecht T, Cookson MW, Giddings Jr. TH, Clarissa C, and Winey M. The two human centrin homologues have similar but distinct functions at Tetrahymena basal bodies. Molecular Biology of the Cell. 2012; 23(24):4766-4777.

  165. Insinna C, Daniele LL, Davis JA, Larsen DD,Kuemmel C, Wang J, Nikonov SS, Knox BE, and Pugh Jr. EN. An S-opsin knockin mouse (F81Y) reveals a role for the native ligand 11-cis retinal in cone opsin biosynthesis. The Journal of Neuroscience. 2012; 32(23):8094-8104.

  166. Voelkel-Meiman K, Moustafa SS, Lefrançois P, Villeneuve AM, MacQueen AJ. Full-Length Synaptonemal Complex Grows Continuously during Meiotic Prophase in Budding Yeast. PLOS GENETICS. 2012: 8(10): e1002993. doi:10.1371/journal.pgen.1002993.

  167. Xu N, Zhang SO, Cole RA, McKinney SA, Guo F, Haas JT, Bobba S, Farese Jr. RV, and Mak HY. The FATP1–DGAT2 complex facilitates lipid droplet expansion at the ER–lipid droplet interface. The Jounal of Cell Biology. 2012: 198(5):895-911.

  168. Qian W, Miki D, Zhang H, Liu Y, Zhang X, Tang K, Kan Y, La H, Li X, Li S, Zhu X, Shi X, Zhang K, Pontes O, Chen X, Liu R, Gong Z, and Zhu J. A Histone Acetyltransferase Regulates Active DNA Demethylation in Arabidopsis. Science. 2012; 336(6087): 1445-1448.

  169. Nguyen CL, Possemato R, Bauerlein1 EL, Xie A, Scully R, and Hahn WC. Nek4 regulates entry into replicative senescence and the response to DNA-damage in human fibroblasts. Molecular and Cellular Biology. doi: 10.1128/​MCB.00436-12.

  170. Peel N, Dougherty M, Goeres M, Liu Y, and O'Connel KF. The C. elegans F-box proteins LIN-23 and SEL-10 antagonize centrosome duplication by regulating ZYG-1 levels. Journal of Cell Science. 2012; 125: 3535-3544.

  171. Martić S, Gabriel M, Turowec JP, Litchfield DW, and Kraatz H. Versatile Strategy for Biochemical, Electrochemical and Immunoarray Detection of Protein Phosphorylations. Journal of the American Chemical Society. 2012; 134 (41), pp 17036–17045.

  172. Wu N, Kong X, Ji Z, Zeng W, Potts PR, Yokomori K, and Yu H. Scc1 sumoylation by Mms21 promotes sister chromatid recombination through counteracting Wapl. Genes and Development. 2012 July 1; 26(13): 1473–1485.

  173. Zhang J, Yu Y, Nakamura K, Koike T, Waqar AB, Zhang X, Liu E, Nishijima K, Kitajima S, Shiomi M, Qi Z, Yu J, Graham MJ, Crooke RM, Ishida T, Hirata K, Hurt-Camejo E, Chen YE, and Fan J. Endothelial Lipase Mediates HDL Levels in Normal and Hyperlipidemic Rabbits. Journal of Atherosclerosis and Thrombosis. 2012;19(3):213-26.

  174. Sporn JC and Jung B. Differential Regulation and Predictive Potential of MacroH2A1 Isoforms in Colon Cancer. The American Journal of Pathology. 2012; 180(6): 2516-2526.

  175. Bhattarai SR, Yoo SY, Lee S, and Dean D. Engineered phage-based therapeutic materials inhibit Chlamydia trachomatis intracellular infection. Biomaterials. 2012; 33:5166-5174.

  176. Thapa A,Morris L, Xu J, Ma H, Michalakis S, Biel M, and Ding X,. Endoplasmic reticulum stress-associated cone photoreceptor degeneration in cyclic nucleotide-gated channel deficiency. The Jounal of Biological Chemistry. 2012; 10.1074/jbc.M112.342220.

  177. Carrieri D, Paddock T, Maness P, Seiberta M, and Yu J. Photo-catalytic conversion of carbon dioxide to organic acids by a recombinant cyanobacterium incapable of glycogen storage. Energy & Environmental Science. 2012; 5:9457-9461.

  178. Beverly LJ, Lockwood WW, Shah PP, Erdjument-Bromage H, Varmus H. Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1 . PNAS. 2012; 10.1073/pnas.1119167109.

  179. Driscoll MK, Albanese JL, Xiong Z, Mailman M, Losert W, and Cao K. Automated image analysis of nuclear shape: What can we learn from a prematurely aged cell? Impact Journal on Aging. 2012; 4(2): 119-132.

  180. Longworth MS, Walker JA, Anderssen E, Moon NS, Gladden A, Heck MMS, Ramaswamy S, and Dyson NJ. A Shared Role for RBF1 and dCAP-D3 in the Regulation of Transcription with Consequences for Innate Immunity. PLOS Genetics. 2012; DOI: 10.1371/journal.pgen.1002618.

  181. Huang WC, Xiao S, Huang F, Harfe BD, Jan YN, Jan LY. Calcium-Activated Chloride Channels (CaCCs) Regulate Action Potential and Synaptic Response in Hippocampal Neurons. Neuron. 2012; 74(1): 179-192.

  182. Ultanir SK, Hertz NT, Li G, Ge W, Burlingame AL, Pleasure SJ, Shokat KM, Jan LY, Jan YN. Chemical Genetic Identification of NDR1/2 Kinase Substrates AAK1 and Rabin8 Uncovers Their Roles in Dendrite Arborization and Spine Development. Neuron. 2012; 73(6): 1127-1142.

  183. Seldin MM, Peterson JM, Byerly MS, Wei Z, and Wong GW. Myonectin (CTRP15), a Novel Myokine That Links Skeletal Muscle to Systemic Lipid Homeostasis. The Journal of Biological Chemistry. 2012; 287: 11968-11980.

  184. Song X, Bowen J, Miao W, Liu Y, and Gorovsky MA. The nonhistone, N-terminal tail of an essential, chimeric H2A variant regulates mitotic H3-S10 dephosphorylation. Genes & Development. 2012; 26: 615-629.

  185. Yang H, Zheng Z, Zhao L, Li Q, and Liao D. Downregulation of Mdm2 and Mdm4 enhances viral gene expression during adenovirus infection. Cell Cycle. 2012; 11(3): 582-593.

  186. Mortensen BL, Fuller JR, Taft-Benz S, Collins EJ, and Kawula TH. Francisella tularensis RipA Protein Topology and Identification of Functional Domains. Journal of Bacteriology. 2012; 194(6): 1474-1484.

  187. Yamakoshi Y, Richardson AS, Nunez SM, Yamakoshi F, Milkovich RN, Hu JC, Bartlett JD, and Simmer JP. Enamel proteins and proteases in Mmp20 and Klk4 null and double-null mice. European Journal of Oral Sciences. 2012; DOI: 10.1111/j.1600-0722.2011.00866.x.

  188. Kulis M, Chen X, Lew J, Wang Q, Patel OP, Zhuang Y, Murray KS, Duncan MW, Porterfield HS, Burks AW, Dreskin SC. The 2S albumin allergens of Arachis hypogaea, Ara h 2 and Ara h 6, are the major elicitors of anaphylaxis and can effectively desensitize peanut-allergic mice. Clinical and Experimental Allergy. 2012; 42(2): 326-336.

  189. McCommis KS, McGee AM, Laughlin MH, Bowles DK, Baines CP. Hypercholesterolemia increases mitochondrial oxidative stress and enhances the MPT response in the porcine myocardium: beneficial effects of chronic exercise.American Journal of Physiology. 2011; 301(5): R1250-R1258.

  190. Cao K, Graziotto JJ, Blair CD, Mazzulli JR, Erdos MR, Krainc D, and Collins FS. Rapamycin Reverses Cellular Phenotypes and Enhances Mutant Protein Clearance in Hutchinson-Gilford Progeria Syndrome Cells. Science Translational Medicine. 2011; doi: 10.1126/scitranslmed.3002346.

  191. Yamakoshi Y, Yamakoshi F, Hu JC, Simmer JP. Characterization of kallikrein-related peptidase 4 glycosylations.European Journal of Oral Sciences. 2011; 119 Suppl 1:234-40. doi: 10.1111/j.1600-0722.2011.00863.x.

  192. Du YN, Chou C, Klimstra D, and Varmus H. Receptor for hyaluronan-mediated motility isoform B promotes liver metastasis in a mouse model of multistep tumorigenesis and a tail vein assay for metastasis. PNAS. 2011; 108(40): 16753-16758.

  193. Chih B, Liu P, Chinn Y, Chalouni C, Komuves LG, Hass PE, Sandoval W, and Peterson AS. A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain. Nature Cell Biology. 2011; doi:10.1038/ncb2410.

  194. Kant S, Swat W, Zhang S, Zhang Z, Neel BG, Flavell RA,Davis RJ. TNF-stimulated MAP kinase activation mediated by a Rho family GTPase signaling pathway. Genes and Development. 2011; 25(19): 2069–2078.

  195. Hsu S, Nafati M, and Inoue K. OEP80, an essential protein paralogous to the chloroplast protein translocation channel Toc75, exists as a 70-kD protein in the Arabidopsis thaliana chloroplast outer envelope. Plant Molecular Biology . 2011; doi: 10.1007/s11103-011-9853-2.

  196. Chen X, Zhuang Y, Wang Q, Moutsoglou D, Ruiz G, Yen SE, and Dreskin SC. Analysis of the Effector Activity of Ara h 2 and Ara h 6 by Selective Depletion from a Crude Peanut Extract. Journal of Immunological Methods. 2011; doi:10.1016/j.jim.2011.06.031.

  197. Zhou M, Hu Q, Li Z, Li D, Chen C, and Luo H. Expression of a Novel Antimicrobial Peptide Penaeidin4-1 in Creeping Bentgrass (Agrostis stolonifera L.) Enhances Plant Fungal Disease Resistance. PLoS ONE. 2011; 6(9): e24677.

  198. Saha RN, Wissink EM, Bailey ER, Zhao M, Fargo DC, Hwang J, Daigle KR, Fenn JD, Adelman K, and Dudek SM. Rapid activity-induced transcription of Arc and other IEGs relies on poised RNA polymerase II. Nature Neuroscience. 2011; 14: 848–856.

  199. Biswas A, Boutaghou MN, Alvey RM, Kronfel CM, Cole RB, Bryant DA, and Schluchter WM. Characterization of the Activities of the CpeY, CpeZ, and CpeS Bilin Lyases in Phycoerythrin Biosynthesis in Fremyella Diplosiphon Strain UTEX 481. The Journal of Biological Chemistry. 2011; doi: 10.1074/jbc.M111.284281.

  200. Castorino JJ, Gallagher-Colombo SM, Levin AV, FitzGerald PG, Polishook J, Kloeckener-Gruissem B, Ostertag E, and Philp NJ. Juvenile Cataract-associated Mutation of Solute Carrier SLC16A12 Impairs Trafficking of the Protein to the Plasma Membrane. Investigative Ophthalmology & Visual Science. 2011; 10-6579.

  201. Singh SK, Brito C, Tan QW, De León M, De León D. Differential Expression and Signaling Activation of Insulin Receptor Isoforms A and B: A Link Between Breast Cancer and Diabetes. Informa Healthcare. 2011; doi:10.3109/08977194.2011.616200.

  202. Wang C, Hennessey JA, Kirkton RD, Wang C, Graham V, Puranam RS, Rosenberg PB, Bursac N, Pitt GS. Fibroblast Growth Factor Homologous Factor 13 Regulates Na+ Channels and Conduction Velocity in Murine Hearts. Circulation Research. 2011; doi: 10.1161/CIRCRESAHA.111.247957.

  203. Ke Y, Huh JW, Warrington R, Li B, Wu N, Leng M, Zhang J, Ball HL, Li B, and Yu H. PICH and BLM Limit Histone Association with Anaphase Centromeric DNA Threads and Promote Their Resolution. The EMBO Journal. 2011; 30, 3309-3321.

  204. Garg S, Sharma M, Ung C, Tuli A, Barral DC, Hava DL, Veerapen N, Besra GS, Hacohen N, and Brenner MB. Lysosomal Trafficking, Antigen Presentation, and Microbial Killing Are Controlled by the Arf-like GTPase Arl8b. Journal of Immunity. 2011; doi:10.1016/j.immuni.2011.06.009.

  205. Cheong H, Lindsten T, Wu J, Lu C, and Thompson CB. Ammonia-induced Autophagy is Independent of ULK1/ULK2 Kinases. PNAS. 2011; doi: 10.1073/pnas.1107969108.

  206. Huang X, Summers MD, Pham V, Lill JR, Liu J, Lee G, Kirkpatrick DS, Jackson PK, Fang G, Dixit VM. Deubiquitinase USP37 Is Activated by CDK2 to Antagonize APCCDH1 and Promote S Phase Entry. Molecular Cell. 2011; 42(4):511-523.

  207. Davis EE, Zhang Q, Liu Q, Diplas BH, Davey LM, Hartley J, Stoetzel C, Szymanska K, Ramaswami G, Logan CV, Muzny DM, Young AC, Wheeler DA, Cruz P, Morgan M, Lewis LR, Cherukuri P, Maskeri B, Hansen NF, Mullikin JC, Blakesley RW, Bouffard GG, Gyapay G, RiegerS, Tönshoff B, Kern I, Soliman NA, Neuhaus TJ, Swoboda KJ, Kayserili H, Gallagher TE, Lewis RA, Bergmann C, Otto EA, Saunier S, Scambler PJ, Beales PL, Gleeson JG, ER Maher, Attié-Bitach T, Dollfus H, Johnson CA, Green ED, Gibbs RA, Hildebrandt F, Pierce EA and Katsanis N. TTC21B Contributes Both Causal and Modifying Alleles Across the Ciliopathy Spectrum. Nature Genetics. 2011; doi:10.1038/ng.756.

  208. Kehat I, Accornero F, Aronow BJ, and Molkentin JD. Modulation of Chromatin Position and Gene Expression by HDAC4 Interaction with Nucleoporins. The Journal of Cell Biology 2011; 193(1): 21-29.

  209. Song MH, Liu Y, Anderson DE, Jahng WJ, and O'Connell KF. Protein Phosphatase 2A-SUR-6/B55 Regulates Centriole Duplication in C. elegans by Controlling the Levels of Centriole Assembly Factors. Developmental Cell 2011: 20(4): 563-571.

  210. Yang Y, Cochran DA, Gargano MD, King I, Samhat NK, Burger BP, Sabourin KR, Hou Y, Awata J, Parry DAD, Marshall WF, Witman GB, and Lu X. Regulation of flagellar motility by the conserved flagellar protein CG34110/Ccdc135/FAP50, Molecular Biology of the Cell. 2011; 22(7): 976-987.

  211. Szuperák M, Salah S, Meyer EJ, Nagarajan U, Ikmi A and Gibson MC. Feedback Regulation of Drosophila BMP Signaling by the Novel Extracellular Protein Larval Translucida. Development. 2011; 138: 715-724.

  212. Mayer PR, Huang N, Dewey CM, Dries DR, Zhang H, and Yu G. Expression, Localization, and Biochemical Characterization of Nicotinamide Mononucleotide Adenylyltransferase 2. The Journal of Biological Chemistry. 2010; 285: 40387-40396.

  213. Hurov KE, Cotta-Ramusino C, and Elledge SJ. A Genetic Screen Identifies the Triple T Complex Required for DNA Damage Signaling and ATM and ATR Stability. Genes and Development. 2010; 24: 1939-1950

  214. Dynek JN, Goncharov T, Dueber EC, Fedorova AV, Izrael-Tomasevic A, Phu L, Helgason E, Fairbrother WJ, Deshayes K, Kirkpatrick DS, and Vucic D. c-IAP1 and UbcH5 Promote K11-linked Polyubiquitination of RIP1 in TNF Signalling The EMBO Journal. 2010; doi:10.1038/emboj.2010.300.

  215. Hanington PC, Forys MA, Dragoo JW, Zhang S, Adema CM, and Loker ES. Role for a somatically diversified lectin in resistance of an invertebrate to parasite infection. PNAS. 2010; 107(49): 21087-21092, doi: 10.1073/pnas.1011242107.

  216. Ai M, Min S, Grosjean Y, Leblanc C, Bell R, Benton R, and Suh1 GSB. Acid Sensing by the Drosophila Olfactory System. Nature. 2010; doi:10.1038/nature09537.

  217. Daniele LL, Insinna C, Chance R, Wang J, Nikonov SS and Pugh Jr. EN. A Mouse M-opsin Monochromat: Retinal Cone Photoreceptors Have Increased M-opsin Expression When S-opsin is Knocked Out. Vision Research. 2010; doi:10.1016/j.visres.2010.12.017.

  218. Gallagher-Colombo1 S, Maminishkis A, Tate S, Grunwald GB, and Philp NJ. Modulation of MCT3 Expression during Wound Healing of the Retinal Pigment Epithelium. Investigative Ophthalmology & Visual Science. 2010; 51:10 5343-5350.

  219. Chun YHP, Lu Y, Hu Y, Krebsbach PH, Yamada Y, Hu JCC, and Simmer JP. Transgenic Rescue of Enamel Phenotype in Ambn Null Mice. Journal of Dental Research. 2010; 10.1177/0022034510379223.

  220. McGee AM and Baines CP. Complement 1q binding protein inhibits the mitochondrial permeability transition pore and protects against oxidative stress-induced death. Biochemical Journal. 2010; doi:10.1042/BJ20101431.

  221. Doyle JM, Gao J, Wang J, Yang M, and Potts PR. MAGE-RING Protein Complexes Comprise a Family of E3 Ubiquitin Ligases. Molecular Cell. 2010; 39:6 963-974, 24.

  222. Emter CA, and Baines CP. Low-Intensity Aerobic Interval Training Attenuates Pathological Left Ventricular Remodeling and Mitochondrial Dysfunction in Aortic-Banded Miniature Swine. American Journal of Physiology - Heart and Circulatory Physiology 2010; doi:10.1152/ajpheart.00578.2010.

  223. Wang X, Hao J, Xie Y, Sun Y, Hernandez B, Yamoah AK, Prasad M, Zhu Q, Feng JQ, and Qin C. Expression of FAM20C in the Osteogenesis and Odontogenesis of Mouse. Journal of Histochemistry and Cytochemistry. 2010; doi:10.1369/jhc.2010.956565.

  224. Smogorzewska A, Desetty R, Saito TT, Schlabach M, Lach FP, Sowa ME, Clark AB, Kunkel TA, Harper JW, Colaiácovo MP, and Elledge SJ. A Genetic Screen Identifies FAN1, a Fanconi Anemia-Associated Nuclease Necessary for DNA Interstrand Crosslink Repair. Molecular Cell. 2010; 39(1): 36-47.

  225. Al-Anzi B, Armand E, Nagamei P, Olszewski M, Sapin V, Waters C, Zinn K, Wyman RJ, and Benzer S. The Leucokinin Pathway and Its Neurons Regulate Meal Size in Drosophila. Current Biology. 2010; 20(11): 969-978.

  226. Gallagher-Colombo S, Maminishkis A, Tate S, Grunwald GB, and Philp NJ. Expression of MCT3 After Wounding of the RPE Requires Re-epithelialization and Restoration of Cell-cell Contact. Investigative Ophthalmology & Visual Science. 2010; doi:10.1167/iovs.09-5028.

  227. Singh SK, Tan QW, Brito C, De León M and De León D. Insulin-like Growth Factors I and II Receptors in the Breast Cancer Survival Disparity Among African–American Women. Growth Hormone & IGF Research. 2010; 20(3) 245-254.

  228. Gao Z, Liu H, Daxinger L, Pontes O, He X, Qian W, Lin H, Xie M, Lorkovic ZJ, Zhang S, Miki1 D, Zhan X, Pontier D, Lagrange T, Jin H, Matzke AJM, Matzke M, Pikaard CS, and Zhu J. An RNA polymerase II- and AGO4-associated Protein Acts in RNA-directed DNA Methylation. Nature. 2010; doi:10.1038/nature09025.

  229. Dou Y, Balse E, Zadeh AD, Wang T, Goonesekara CL, Noble GP, Eldstrom J, Steele DF, Hatem SN, and Fedida D. Normal Targeting of a Tagged Kv1.5 Channel Acutely Transfected into Fresh Adult Cardiac Myocytes by a Biolistic Method. American Journal of Physiology - Cell Physiology. 2010; doi:10.1152/ajpcell.00005.2010.

  230. Vanzin G, Yu J, Smolinski S, Tek V, Pennington G, and Maness P. Characterization of Genes Responsible for the CO-linked Hydrogen-Production Pathway in Rubrivivax gelatinosus. Applied and Environmental Microbiology. 2010; doi:10.1128/AEM.02753-09.

  231. Raleigh DR, Marchiando AM, Zhang Y, Shen L, Sasaki H, Wang Y, Long M, and Turner JR. Tight Junction–associated MARVEL Proteins MarvelD3, Tricellulin, and Occludin Have Distinct but Overlapping Functions. Molecular Biology of the Cell. 2010; 21(7): 1200-1213.

  232. Gundersen CB, Kohan SA, Souda P, Whitelegge JP, and Umbach JA. Cysteine String Protein β is Prominently Associated with Nerve Terminals and Secretory Organelles in Mouse Brain. Brain Research. 2010: doi:10.1016/j.brainres.2010.03.044.

  233. Kim S, Wairkar YP, Daniels RW, DiAntonio A. The novel endosomal membrane protein Ema interacts with the class C Vps–HOPS complex to promote endosomal maturation. The Journal of Cell Biology. 2010; doi:10.1083/jcb.200911126.

  234. Valdivia CR, Medeiros-Domingo A, Ye B, Shen W, Algiers TJ, Ackerman MJ, and Makielski JC. Loss-of-function Mutation of the SCN3B-encoded Sodium Channel β3 Subunit Associated with a Case of Idiopathic Ventricular Fibrillation. Cardiovascular Research. 2010; 0: cvp417v2-cvp417.

  235. Camahort R, Shivaraju M, Mattingly M, Li B, Nakanishi S, Zhu D, Shilatifard A, Workman JL, and Gerton JL. Cse4 is Part of an Octameric Nucleosome in Budding Yeast. Molecular Cell. 2010; 35:6 794-805.

  236. Singh SK, Tan QW, Brito C, De León, M, Garberoglio C, and De León D. Differential insulin-like growth factor II (IGF-II) expression: A potential role for breast cancer survival disparity. Growth Hormone & IGF Research. 2009; 20(2): 162-170.

  237. Nakayama H, Bodi I, Correll RN, Chen X, Lorenz J, Houser SR, Robbins J, Schwartz A, and Molkentin JD. α1G-dependent T-type Ca2+ current antagonizes cardiac hypertrophy through a NOS3-dependent mechanism in mice. Journal of Clinical Investigation. 2009; 119(2): 3787-3796.

  238. He XJ, Hsu YF, Zhu S, Liu HL, Pontes O, Zhu J, Cui X, Wang CS, and Zhu JK. A conserved transcriptional regulator is required for RNA-directed DNA methylation and plant development. Genes and Development. 2009; 23:2717-2722.

  239. Parry JM, Velarde NV, Lefkovith AJ, Zegarek MH, Hang JS, Ohm J, Klancer R, Maruyama R, Druzhinina MK, Grant BD, Piano F, and Singson A. EGG-4 and EGG-5 Link Events of the Oocyte-to-Embryo Transition with Meiotic Progression in C. elegans. Cell Current Biology. 2009; 19(20): 1752-1757; DOI:

  240. Isaac J, Hartney SL, Druffel K, and Hadwiger LA. The non-host disease resistance response in peas; alterations in phosphorylation and ubiquitination of HMG A and histones H2A/H2B. Plant Science. 2009; 177:5 439-449.

  241. Chen F, Shim H, Morhardt D, Dallman R, Krahn E, McWhinney L, Rao A, Gold S, and Chen CK. Functional Redundancy of R7 RGS Proteins in ON-bipolar Cell Dendrites. Investigative Ophthalmology and Visual Science. 2009; 09-4084.

  242. Nagano T, Kakegawa A, Yamakoshi Y, Tsuchiya S, Hu JCC, Gomi K, Arai T, Bartlett JD and Simmer JP. Mmp-20 and Klk4 Cleavage Site Preferences for Amelogenin Sequences. Journal of Dental Research. 2009; 88(9): 823-828.

  243. Simmer JP, Hu Y, Lertlam R, Yamakoshi Y, and Hu JCC. Hypomaturation Enamel Defects in Klk4 Knockout/LacZ Knockin Mice. Journal of Biological Chemistry. 2009; 284(28): 19110-19121.

  244. Khanna H, Davis EE, Murga-Zamalloa CA, Estrada-Cuzcano A, Lopez I, den Hollander AI, Zonneveld MN, Othman MI, Waseem N, Chakarova CF, Maubaret C, Diaz-Font A, MacDonald I, Muzny DM, Wheeler DA, Morgan M, Lewis LR, Logan CV, Tan PL, Beer MA, Inglehearn CF, Lewis RA, Jacobson SG, Bergmann C, Beales PL, Attié-Bitach T, Johnson CA, Otto EA, Bhattacharya SS, Hildebrandt F, Gibbs RA, Koenekoop RK, Swaroop A & Katsanis N. A Common Allele in RPGRIP1L is a Modifier of Retinal Degeneration in Ciliopathies. Nature Genetics. 2009; 41:739-745.

  245. Gao L, Pung YF, Zhang J, Chen P, Wang T, Li M, Meza M, Toro L, and Cai HL. Sepiapterin Reductase Regulation of Endothelial Tetrahydrobiopterin and Nitric Oxide Bioavailability. American Journal of Physiology-Heart and Circulatory Physiology. 2009; 297: H331-H339.

  246. Misaghi S, Ottosen S, Izrael-Tomasevic A, Arnott D, Lamkanfi M, Lee J, Liu J, O'Rourke K, Dixit VM, and Wilson AC. Association of C-Terminal Ubiquitin Hydrolase BRCA1-Associated Protein 1 with Cell Cycle Regulator Host Cell Factor 1. Molecular and Cellular Biology. 2009; 29(8):2181-2192.

  247. Guelman S, Kozuka K, Mao Y, Pham V, Solloway M, Wang J, Wu J, Lill JR, and Zha J. The Double-Histone-Acetyltransferase Complex ATAC Is Essential for Mammalian Development. Molecular and Cellular Biology. 2009; 29(5):1176-1188.

  248. Kim AH, Puram SV, Bilimoria PM, Ikeuchi Y, Keough S, Wong M, Rowitch D, and Bonni A. A Centrosomal Cdc20-APC Pathway Controls Dendrite Morphogenesis in Postmitotic Neurons. Cell. 2009; 136(2):322-336.

  249. Liu Q, Busby JC, and Molkentin JD. Interaction between TAK1–TAB1–TAB2 and RCAN1–calcineurin defines a signalling nodal control point. Nature Cell Biology. 2009; 11: 154-161. doi:10.1038/ncb1823.

  250. Jung C, Jun C, Ro S, Kim Y, Otto NM, Cao J, Kundu M, and Kim D. ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery. Molecular Biology of the Cell. 10.1091/mbc.E08-12-1249.

  251. Gocke C, Yu H. ZNF198 Stabilizes the LSD1–CoREST–HDAC1 Complex on Chromatin through Its MYM-Type Zinc Fingers. PLoS ONE. 2008; 3(9):e3255.

  252. Li S, Jin Z, Koirala S, Bu L, Xu L, Hynes RO, Walsh CA, Corfas G, and Piao X. GPR56 Regulates Pial Basement Membrane Integrity and Cortical Lamination. The Journal of Neuroscience. 2008; 28(22):5817–5826.

  253. Wang Z and Sun Y. Identification and Characterization of Two Splicing Variants of Human Noxa. Anticancer Research. 2008; 28:3A 1667-1674.

  254. Yudin AI, Tollner TL, Treece CA, Kays R, Cherr GN, Overstreet1 JW, and Bevins CL. β-Defensin 22 is a major component of the mouse sperm glycocalyx. Reproduction. 2008; 136:753-765.

  255. Soupene E, Serikov V, and Kuypers FA. Characterization of an acyl-coenzyme A binding protein predominantly expressed in human primitive progenitor cells. Journal of Lipid Research. 2008; 49:1103-1112.

  256. Woo S, Kim D, Jun C, Kim Y, Vander Haar E, Lee S, Hegg JW, Bandhakavi S, Griffin TJ, and Kim D. PRR5, A Novel Component of mTOR Complex 2, Regulates PDGFRβ Expression and Signaling. Journal of Biological Chemistry. 2007; 282(35): 25604-25612.

  257. (anti-PTM antibodies)

  258. Kumar S, Kim Y-R, Vikram A, Naqvi A, Li Q, Kassan M, Kumar V, Bachschmid MM, Jacobs JS, Kumar A, and Irani K. Sirtuin1-regulated lysine acetylation of p66Shc governs diabetes-induced vascular oxidative stress and endothelial dysfunction. PNAS. 2017; 114(7): 1714-1719. doi: 10.1073/pnas.1614112114.

  259. Zhang Z, Newton K, Kummerfeld SK, Webster J, Kirkpatrick DS, Phu L, Eastham-Anderson J, Liu J, Lee WP, Wu J, Li H, Junttila MR, and Dixit VM. Transcription factor Etv5 is essential for the maintenance of alveolar type II cells. PNAS. 2017; doi: 10.1073/pnas.1621177114.

  260. Martina JA, Diab HI, Brady OA, Puertollano R. TFEB and TFE3 are novel components of the integrated stress response. The EMBO Journal. 2017; 36(5): 565-702; DOI 10.15252/embj.201593428.

  261. Yadav S, Oses-Prieto JA, Peters CJ, Zhou J, Pleasure SJ, Burlingame AL, Jan LY and Jan Y. TAOK2 Kinase Mediates PSD95 Stability and Dendritic Spine Maturation through Septin7 Phosphorylation. Neuron. 2017; 93: 1-15.

  262. Wein MN, Liang Y, Goransson O, Sundberg TB, Wang J, Williams EA, O’Meara MJ, Govea N, Beqo B, Nishimori S, Nagano K, Brooks DJ, Martins JS, Corbin B, Anselmo A, Sadreyev R, Wu JY, Sakamoto K, Foretz M, Xavier RJ, Baron R, Bouxsein ML, Gardella TJ, Divieti-Pajevic P, Gray NS, and Kronenberg HM. SIKs control osteocyte responses to parathyroid hormone. Nature Communications 2016; doi:10.1038/ncomms13176.

  263. Pulido MA, DerHartunian MK, Qin Z, Chung EM, Kang DS, Woodham AW, Tsou JA, Klooster R, Akbari O, Wang L, Kast WM, Liu SV, Verschuuren JJGM, Aswad DW, and Laird-Offringa IA. Isoaspartylation appears to trigger small cell lung cancer-associated autoimmunity against neuronal protein ELAVL4. Journal of Neuroimmunology. 2016; 299: 70-78.

  264. Tunc-Ozdemir M, Urano D, Jaiswal DK, Clouse SD, and Jones AM. Direct Modulation of Heterotrimeric G Protein-coupled Signaling by a Receptor Kinase Complex. The Journal of Biological Chemistry.2016; 291: 13918-13925. doi: 10.1074/jbc.C116.736702.

  265. Shatz W, Hass P, Mathieu M, Kim HS, Leach K, Zhou M, Crawford Y, Shen A, Wang K, Chang DPS, Maia M, Crowell S, Dickmann L, Scheer J, and Kelley RF. Contribution of Antibody Hydrodynamic Size to Vitreal Clearance Revealed Through Rabbit Studies Using a Species-Matched Fab. Molecular Pharmaceutics. 2016; DOI: 10.1021/acs.molpharmaceut.6b00345.

  266. Lee SB, Frattini V, Bansal M, Castano AM, Sherman D, Hutchinson K, Bruce JN, Califano A, Liu G, Cardozo T, Iavarone A, and Lasorella A. An ID2-dependent mechanism for VHL inactivation in cancer. Nature. 2016; 529: 172-177; doi:10.1038/nature16475 .

  267. Mo F, Zhuang X, Liu X, Yao PY, Qin B, Su Z, Zang J, Wang Z, Zhang J, Dou Z, Tian C, Teng M, Niu L, Hill DL, Fang G, Ding X, Fu C, and Yao X. Acetylation of Aurora B by TIP60 ensures accurate chromosomal segregation. Nature Chemical Biology. 2016; doi:10.1038/nchembio.2017.

  268. Martina JA, Diab HI, Brady OA, and Puertollano R. TFEB and TFE3 are novel components of the integrated stress response. The EMBO Journal. 2016; DOI: 10.15252/embj.201593428.

  269. Lin A, Li C, Xing Z, Hu Q, Liang K, Han L, Wang C, Hawke DH, Wang S, Zhang Y, Wei Y, Ma G, Park PK, Zhou J, Zhou Y, Hu Z, Zhou Y, Marks JR, Liang H, Hung M, Lin C, and Yang L. The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer. Nature Cell Biology. 2016; 18: 213-224; doi:10.1038/ncb3295.

  270. Sunkel B, Wu D, Chen Z, Wang C, Liu X, Ye Z, Horning AM, Liu J, Mahalingam D, Lopez-Nicora H, Lin C, Goodfellow PJ, Clinton SK, Jin VX, Chen C, Huang TH, and Wang Q. Integrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence. Nucleic Acids Research. 2016; doi: 10.1093/nar/gkv1528.

  271. Zhai Q, He M, Song A, Deshayes K, Dixit VM, Carter PJ. Structural Analysis and Optimization of Context-Independent Anti-Hypusine Antibodies. Journal of Medical Biology. 2016; doi:10.1016/j.jmb.2016.01.006.

  272. Lee J, Peng Y, Lin W, Parrish JZ. Coordinate control of terminal dendrite patterning and dynamics by the membrane protein Raw. Development. 2015; 142: 162-173. doi: 10.1242/dev.113423.

  273. Shehata SN, Deak M, Morrice NA, Ohta E, Hunter RW, Kalscheuer VM, and Sakamoto K. Cyclin Y Phosphorylation- and 14-3-3-binding-dependent Activation of PCTAIRE-1/CDK16. Biochemical Journal. 2015; DOI: 10.1042/BJ20150486.

  274. Chen Y, Jones MJK, Yin Y, Crist SB, Colnaghi L, Sims III RJ, Rothenberg E, Jallepalli PV, Huang TT. ATR-Mediated Phosphorylation of FANCI Regulates Dormant Origin Firing in Response to Replication Stress. Molecular Cell. 2015; 58(2): 323-338.

  275. Gunawan M, Venkatesan N, Loh JT, Wong JF, Berger H, Neo WH, Li LYJ, Win MKL, Yau YH, Guo T, See PCE, Yamazaki S, Chin KC, Gingras AR, Shochat SG, Ng LG, Sze SK, Ginhoux F, and Su I. The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin. Nature Immunology. 2015; (Supp)16: 505-516. doi:10.1038/ni.3125.

  276. Perlini LE, Szczurkowska J, Ballif BA, Piccini A, Sacchetti S, Giovedì S, Benfenati F, Cancedda L. Synapsin III Acts Downstream of Semaphorin 3A/CDK5 Signaling to Regulate Radial Migration and Orientation of Pyramidal Neurons In Vivo. Cell Reports. 2015; 11: 1-15. doi:10.1016/j.celrep.2015.03.022.

  277. Ducommun S, Deak M, Sumpton D, Ford RJ, Galindo AN, Kussmann M, Viollet B, Steinberg GR, Foretz M, Dayon L, Morrice NA, Sakamoto K. Motif affinity and mass spectrometry proteomic approach for the discovery of cellular AMPK targets: Identification of mitochondrial fission factor as a new AMPK substrate. Cellular Signaling. 2015; doi:10.1016/j.cellsig.2015.02.008.

  278. Crawley CD, Kang S, Bernal GM, Wahlstrom JS, Voce DJ, Cahill KE, Garofalo A, Raleigh DR, Weichselbaumb RR, and Yamini B. S-phase-dependent p50/NF-кB1 phosphorylation in response to ATR and replication stress acts to maintain genomic stability. Cell Cycle. 2015; 14(4): 566-576. DOI:10.4161/15384101.2014.991166.

  279. Pagan JK, Marzio A, Jones MKJ, Saraf A, Jallepalli PV, Florens L, Washburn MP, and Pagano M. Degradation of ​Cep68 and ​PCNT cleavage mediate ​Cep215 removal from the PCM to allow centriole separation, disengagement and licensing. Nature Cell Biology. 2015; 17: 31-43. doi:10.1038/ncb3076.

  280. Drake M, Furuta T, Suen KM, Gonzalez G, Liu B, Kalia A, Ladbury JE, Fire AZ, Skeath JS, and Arur S. A Requirement for ERK-Dependent Dicer Phosphorylation in Coordinating Oocyte-to-Embryo Transition in C. elegans. Developmental Cell. 2014; 31(5): 614-628. DOI:

  281. Zulliger R, Naash MI, Rajala RVS, Molday RS, and Azadi S. Impaired Association of Retinal Degeneration-3 with Guanylate Cyclase-1 and Guanylate Cyclase-activating Protein-1 Leads to Leber Congenital Amaurosis-1. The Journal of Biological Chemistry. 2014. doi: 10.1074/jbc.M114.616656.

  282. Xing Z, Lin A, Li C, Liang K, Wang S, Liu Y, Park PK, Qin L, Wei Y, Hawke DH, Hung MC, Lin C, Yang L. lncRNA Directs Cooperative Epigenetic Regulation Downstream of Chemokine Signals. Cell. 2014; 159(5): 1110-1125; DOI:

  283. Ultanir SK, Yadav M, Hertz NT, Oses-Prieto JA, Claxton S, Burlingame AL, Shokat KM, Jan LY, Jan YN. MST3 Kinase Phosphorylates TAO1/2 to Enable Myosin Va Function in Promoting Spine Synapse Development. Neuron. 2014; doi:10.1016/j.neuron.2014.10.025.

  284. Patel K, Foretz M, Marion A, Campbell DG, Gourlay R, Boudaba N, Tournier E, Titchenell P, Peggie M, Deak M, Wan M, Kaestner KH, Göransson O, Viollet B, Gray NS, Birnbaum MJ, Sutherland C, and Sakamoto K. The ​LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver. Nature. 2014; doi:10.1038/ncomms5535.

  285. Mazur PK, Reynoird N, Khatri P, Jansen PWTC, Wilkinson AW, Liu S, Barbash O, Van Aller GS, Huddleston M, Dhanak D, Tummino PJ, Kruger RG, Garcia BA, Butte AJ, Vermeulen M, Sage J, and Gozani O. SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer. Nature. 2014; doi:10.1038/nature13320.

  286. Wu L, Li L, Zhou B, Qin Z, Dou Y. H2B Ubiquitylation Promotes RNA Pol II Processivity via PAF1 and pTEFb. Molecular Cell. 2014; 54(6): 920-931.

  287. North BJ, Rosenberg MA, Jeganathan KB, Hafner AV, Michan S, Dai J, Baker DJ, Cen Y, Wu LE, Sauve AA, van Deursen JM, Rosenzweig A, and Sinclair DA. SIRT2 induces the checkpoint kinase BubR1 to increase lifespan. The EMBO Journal. 2014; DOI: 10.15252/embj.201386907.

  288. Cooper LL, Li W, Lu Y, Centraccio J, Terentyeva R, Koren G, and Terentyev D. Redox modification of ryanodine receptors by mitochondria-derived reactive oxygen species contributes to aberrant Ca2+ handling in ageing rabbit hearts. The Journal of Physiology. 2013; doi: 10.1113/jphysiol.2013.260521.

  289. Schulz EM, Wilder T, Chowdhury SAK, Sheikh HN, Wolska BM, Solaro RJ, and Wieczorek DF. Decreasing Tropomyosin Phosphorylation Rescues Tropomyosin-induced Familial Hypertrophic Cardiomyopathy. The Journal of Biological Chemistry. 2013; 288: 28925-28935. doi: 10.1074/jbc.M113.466466.

  290. Zhu H, Carpenter RL, Han W, Lo H. The GLI1 splice variant TGLI1 promotes glioblastoma angiogenesis and growth. Cancer Letters. 2013; doi:10.1016/j.canlet.2013.09.014.

  291. Scholten A, Preisinger C, Corradini E, Bourgonje VJ, Hennrich ML, van Veen TAB, Swaminathan PD, Joiner M, Vos MA, Anderson ME, and Heck AJR. Phosphoproteomics Study Based on In Vivo Inhibition Reveals Sites of Calmodulin‐Dependent Protein Kinase II Regulation in the Heart.Journal of the American Heart Association. 2013; doi: 10.1161/JAHA.113.000318.

  292. Lee EK, Lian Z, D’Andrea K, Letrero R, Sheng WQ, Liu S, Diehl JN, Pytel D, Barbash O, Schuchter L, Amaravaradi R, Xu X, Herlyn M, Nathanson KL, and Diehl JA. Molecular and Cellular Biology. 2013; 33(22): 4422-4433.

  293. Prasad AM, Nuno DW, Koval OM, Ketsawatsomkron P, Li W, Li H, Shen FY, Joiner MA, Kutschke W, Weiss RM, Sigmund CD, Anderson ME, Lamping KG, and Grumbach IM. Differential control of calcium homeostasis and vascular reactivity by Ca2+/calmodulin-dependent kinase II. Hypertension. 2013; (Suppl) 62(2):434-41. doi: 10.1161/HYPERTENSIONAHA.113.01508.

  294. Belevych AE, Ho H, Terentyeva R, Bonilla IM, Terentyev D, Carnes CA, Gyorke S, Billman GE. Dietary Omega-3 Fatty Acids Promote Arrhythmogenic Remodeling of Cellular Ca2+ Handling in a Postinfarction Model of Sudden Cardiac Death. PLoS ONE. 2013; 8(10): e78414. doi:10.1371/journal.pone.0078414.

  295. Petit CS, Roczniak-Ferguson A, and Ferguson SM. Recruitment of folliculin to lysosomes supports the amino acid–dependent activation of Rag GTPases. The Journal of Cell Biology. 2013; 202(7): 1107-1122.

  296. Morawski PA, Mehra P, Chen C, Bhatti T, and Wells AD. Foxp3 Protein Stability Is Regulated by Cyclin-dependent Kinase 2. The Journal of Biological Chemistry. 2013; 288: 24494-24502.

  297. Jin F, Irshad S, Yu W, Belakavadi M, Chekmareva M, Ittmann MM, Abate-Shen C, and Fondell JD. ERK and AKT Signaling Drive MED1 Overexpression in Prostate Cancer in Association with Elevated Proliferation and Tumorigenicity.Molecular Cancer Research. 2013; doi: 10.1158/1541-7786.MCR-12-0618

  298. Wu SY, Lee AY, Lai HT, Zhang H, Chiang CM. Phospho Switch Triggers Brd4 Chromatin Binding and Activator Recruitment for Gene-Specific Targeting. Molecular Cell. 2013; 49(5):843-857.

  299. Shehab MA, Iosef C, Wildgruber R, Sardana G, and Gupta MB. Phosphorylation of IGFBP-1 at Discrete Sites Elicits Variable Effects on IGF-I Receptor Autophosphorylation. Endocrinology. 2013; doi: 10.1210/en.2012-1962

  300. Kochanek DM, and Wells DG. CPEB1 Regulates the Expression of MTDH/AEG-1 and Glioblastoma Cell Migration. Molecular Cancer Research. 2013; doi: 10.1158/1541-7786.MCR-12-0498

  301. Lo YH, Ho PC, Chen MS, Hugo E, Ben-Jonathan N, Wang SC. Phosphorylation at tyrosine 114 of Proliferating Cell Nuclear Antigen (PCNA) is required for adipogenesis in response to high fat diet. Biochemical and Biophysical Research Communications. 2013; 430(1): 43-48.

  302. Schulz EM, Correll RN, Sheikh HJ, Lofrano-Alves MS, Engel PL, Newman G, Schultz JEJ, Molkentin JD, Wolska BM, Solaro RJ, and Wieczorek DF. Tropomyosin Dephosphorylation Results in Compensated Cardiac Hypertrophy. The Journal of Biological Chemistry. 2012; 287: 44478-44489. doi: 10.1074/jbc.M112.402040.

  303. Sheng Z, Zhang S, Bustos D, Kleinheinz T, Le Pichon CE, Dominguez SL, Solanoy HO, Drummond J, Zhang X, Ding X, Cai F, Song Q, Li X, Yue Z, van der Brug MP, Burdick DJ, Gunzner-Toste J, Chen H, Liu X, Estrada AA, Sweeney ZK, Scearce-Levie K, Moffat JB, Kirkpatrick DS, and Zhu H. Ser1292 Autophosphorylation Is an Indicator of LRRK2 Kinase Activity and Contributes to the Cellular Effects of PD Mutations. Science Translational Medicine. 2012; DOI: 10.1126/scitranslmed.3004485.

  304. Hermanson SB, Carlson CB, Riddle SM, Zhao J, Vogel KW, Nichols RJ, and Bi K. Screening for Novel LRRK2 Inhibitors Using a High-Throughput TR-FRET Cellular Assay for LRRK2 Ser935 Phosphorylation. PLoS ONE. 2012; 7(8):e43580.doi:10.1371/journal.pone.0043580.

  305. Guo Y, Kim C, Ahmad S, Zhang J, and Mao Y. CENP-E–dependent BubR1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint. The Journal of Cell Biology. 2012; doi: 10.1083/jcb.201202152.

  306. Van Aller GS, Reynoird N, Barbash O, Huddleston M, Liu S, Zmoos A, McDevitt P, Sinnamon R, Le B, Mas G, Annan R, Sage J, Garcia BA, Tummino PJ, Gozani O, and Kruger RG. Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation. Epigenetics. 2012; 7(4): 340–343. doi: 10.4161/epi.19506.

  307. Schwarz MA, Thornton J, Xu H, Awasthi N, and Schwarz RE. Cell Proliferation and Migration Are Modulated by Cdk-1-Phosphorylated Endothelial-Monocyte Activating Polypeptide II. PLos ONE. 2012; 7(3): e33101. doi:10.1371/journal.pone.0033101.

  308. Leboucher GP, Tsai YC, Yang M, Shaw KC, Zhou M, Veenstra TD, Glickman MH, and Weissman AM. Stress-induced phosphorylation and proteasomal degradation of mitofusin 2 facilitates mitochondrial fragmentation and apoptosis. Molecular Cell. 2012; 47(4): 547-557. doi: 10.1016/j.molcel.2012.05.041

  309. Urano D, Phan N, Jones JC, Yang J, Huang J, Grigston J, Taylor JP, and Jones AM. Endocytosis of the seven-transmembrane RGS1 protein activates G-protein-coupled signalling in Arabidopsis. Nature Cell Biology. 2012; doi:10.1038/ncb2568.

  310. Kang M, Chung J, and Ryoo HD. CDK5 and MEKK1 mediate pro-apoptotic signalling following endoplasmic reticulum stress in an autosomal dominant retinitis pigmentosa model. Nature Cell Biology. 2012; 14: 409-415.

  311. Guise AJ, Greco TM, Zhang IY, Yu F, and Cristea IM. Aurora B-dependent regulation of class IIa histone deacetylases by mitotic nuclear localization signal phosphorylation. Molecular and Cellular Proteomics. 2012; doi: 10.1074/mcp.M112.021030.

  312. Doggett, EA, Zhao, J, Mork, CN, Hu, D, and Nichols, RJ. Phosphorylation of LRRK2 serines 955 and 973 is disrupted by Parkinson’s disease mutations and LRRK2 pharmacological inhibition. Journal of Neurochemistry. 2012; 120(1):37–45.

  313. Harleton E, Besana A, Comas GM, Danilo Jr P, Rosen TS, Argenziano M, Rosen MR, Robinson RB, and Feinmark SJ. Ability to Induce Atrial Fibrillation in the Peri-operative Period Is Associated with Phosphorylation-dependent Inhibition of TWIK Protein-related Acid-sensitive Potassium Channel 1 (TASK-1). The Journal of Biological Chemistry. 2012; 288: 2829-2838.

  314. Zhao Y, Xiong X, Sun Y. DEPTOR, an mTOR Inhibitor, Is a Physiological Substrate of SCFβTrCP E3 Ubiquitin Ligase and Regulates Survival and Autophagy. Molecular Cell. 2011; doi:10.1016/j.molcel.2011.08.029.

  315. Vaites LP, Lee EK, Lian Z, Barbash O, Roy D, Wasik M, Klein-Szanto AJP, Rustgi AK, and Diehl JA. The Fbx4 Tumor Suppressor Regulates Cyclin D1 Accumulation and Prevents Neoplastic Transformation. Molecular and Cellular Biology 2011; doi:10.1128/MCB.05733-11

  316. Gyenis L, Duncan JC, Turowec JP, Bretner M, and Litchfield DW. Unbiased Functional Proteomics Strategy for Protein Kinase Inhibitor Validation and Identification of Bona Fide Protein Kinase Substrates: Application to Identification of EEF1D as a Substrate for CK2. Journal of Proteome Research 2011; doi: 10.1021/pr2008994.

  317. Caldwell GB, Howe AK, Nick CK, Dostmann WR, Ballif BA, Deming PB. Direct Modulation of the Protein Kinase a Catalytic Subunit α by Growth Factor Receptor Tyrosine Kinases. Journal of Cellular Biochemistry. 2011; doi: 10.1002/jcb.23325.

  318. Hafner AV, Dai J, Gomes AP, Xiao CY, Palmeira CM, Rosenzweig A, and Sinclair DA. Regulation of the mPTP by SIRT3-mediated Deacetylation of CypD at Lysine 166 Suppresses Age-related Cardiac Hypertrophy. Aging. 2010; 2:12 914-923.

  319. Aggarwal P, Vaites LP, Kim JK, Mellert H, Gurung B, Nakagawa H, Herlyn M, Hua X, Rustgi AK, McMahon SB, and Diehl JA. Nuclear Cyclin D1/CDK4 Kinase Regulates CUL4 Expression and Triggers Neoplastic Growth via Activation of the PRMT5 Methyltransferase. Cancer Cell 2010; 18:4 329-340.

  320. Kyriss MNM, Jin Y, Gallegos IJ, Sanford JA, and Wyrick JJ. Novel functional residues in the core domain of histone H2B regulate yeast gene expression and silencing and affect the response to DNA damage. Mol. Cell. Biol. 2010; 30(14) 3503-3518.

  321. Liu Q, Busby JC, Molkentin JD. Interaction between TAK1-TAB1-TAB2 and RCAN1-calcineurin Defines a Signalling Nodal Control Point. Nature Cell Biology. 2009; 11(2):154-161.

  322. MacDonnell SM, Weisser-Thomas J, Kubo H, Hanscome M, Liu Q, Jaleel N, Berretta R, Chen X, Brown JH, Sabri A, Molkentin JD and Houser SR. CaMKII Negatively Regulates Calcineurin NFAT Signaling in Cardiac Myocytes. Circulation Research. 2009; 105:316-325.

  323. Lin D, Aggrawal P, Diehl JA. Phosphorylation of MCM3 on Ser-112 regulates its incorporation into the MCM2–7 complex. PNAS. 2008; 105(23):8079-8084.

  324. Barbash O, Zamfirova P, Lin DI, Chen X, Yang K, Nakagawa H, Lu F, Rustgi A, Diehl JA. Mutations in Fbx4 Inhibit Dimerization of the SCFFbx4 Ligase and Contribute to Cyclin D1 Overexpression in Human Cancer. Cancer Cell. 2008; 14(1):68-78.




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